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Theranostics discovered the role and mechanism of liver miR-378 in regulating serum total cholesterol

 Last Update: 2021-08-11
 Source: Internet
 Author: User

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On February 25, 2021, Ying Hao's research group at the Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences published a research result entitled "Hepatic miR-378 modulates serum cholesterol levels by regulating hepatic bile acid synthesis" in Theranostics , and applied for Two patents (202110098302.

Thyroid hormone has a strong cholesterol-lowering effect, and revealing its mechanism of regulating cholesterol metabolism will help to find new strategies for the treatment of hypercholesterolemia

Figure 1 The mechanism of liver miR-378 regulated by TH in regulating cholesterol and bile acid metabolism

Doctoral students Sun Chao and Dr.

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