This paper reveals the mechanism of cooperative evolution and stability in the bacteria aureus.

A cross-scientific study by Professor Jin Fan of the National Research Center for Microscale Material Science in Hefei University of Science and Technology of China reveals the mechanism of cooperative evolution and stability in elitiscobacteria.
the results were published in Nature Communications, an international authoritative academic journal.
is a kind of conditional pathogenic bacteria widely found in nature.
during the infection of the bacteria, the iron in the host body is bound by the ferritin produced by the host, which prevents the bacteria from being ingested and used, which causes the bacteria to grow and replicate in the host body.
, the bacteria are produced through a unique cooperative model, secreting a common iron carrier to help bacteria ingest the key nutrient iron.
however, this synthetic (selfless) bacterial behavior is not yet stable in its evolution and is vulnerable to selfish, i.e. invasion by bacteria that do not produce iron-carrying bacteria, which eventually leads to the collapse of cooperation.
understanding the especial mechanism of pneumococcal bacteria has important clinical significance for how to maintain stability without being invaded by selfish bacteria.
researchers have found that when bacteria tend to share common products when they have less environmental tension, selfless bacteria can be replaced by selfish bacteria.
but once the external environment deteriorates, such as ultraviolet rays, antibiotics, immune response, etc., bacteria will actively reduce the exletum of public products to privatize iron-bearing, these privatized substances can help bacteria resist environmental tension to tide over the difficulties, selfish bacteria because there is no protection of iron-carrying and eliminated.
this peculiar strategy is called "conditional privatization".
researchers have followed up with evolutionary experiments and theoretical calculations to show that conditional privatization can protect bacteria from self-serving bacteria. The clarification of the conditional privatization mechanism of
is of great significance for understanding the origin, evolution and stability of microbial cooperation, and at the same time provides interesting new ideas for the treatment of the infection of leptobacteria-mediated bacteria, that is, by interfering with conditional privatization, the use of "endless" means to destroy and disrupt the cooperation between bacteria, thereby removing pathogenic bacteria in the host.
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