To prevent depression and become a master of emotional management, you may first have to have a good stomach

depression is a mental illness that affects more than 264 million people of all ages worldwide. Understanding its mechanisms is critical to developing effective treatment strategies.symptoms of depression are heterogeneity, the causes of which are diverse, and it is very difficult to fully understand the specific pathology of depression., however, many studies have shown that changes in the structure of the sea mass play a vital role in the pathogenesis of depression. The decrease of sea mass is one of the characteristics of clinical depression. Similarly, studies of rodents have shown that chronic stress depression can damage the nerves of adult sea horses.a recent study by scientists at the Pasteur Institute, the French National Institute of Health and Medical Research and the French National Centre for Scientific Research (CNRS) showed that imbalances in the gut bacterial community can lead to a decrease in certain metabolites, leading to depression-like behavior. These findings suggest that a healthy gut microbiome contributes to normal brain function.the study has been published in the journal Nature Communications.population of bacteria in the gut, known as the gut microbiome, is the largest bacterial population in the body. A growing body of research shows that the host and gut microbiome are mutually beneficial.past decade, the impact of the symbic microbiome on many host functions has become more and more recognized. A variety of gut microorganisms affect many processes, including immunity, metabolism, and the central nervous system.recent observations have also revealed a link between mood disorders and damage to the gut microbiome.a team from all three agencies, they found a correlation between the efficacy of the gut microbiome and fluoxetine, a molecule often used as an antidepressant. But some mechanisms for controlling depression are still unknown.using animal models, the scientists found that changes in the gut microbiome caused by chronic stress can lead to depressive behavior, especially by causing a decrease in lipid metabolites (small molecules produced by metabolism) in the blood and brain.these lipid metabolites, known as endogenetic cannabinin, coordinate a communication system in the body that is significantly hampered by a decrease in metabolites.microbiome disorders caused by chronic stress affect lipid metabolism and endogenetic cannabinin production, leading to a decrease in signal transduction in the cannabinin system and a decrease in the hema nerve.may be part of the reason for linking microbiome disorders to mood disorders. Mood disorders, in turn, can affect the composition of the gut microbiome through physiological regulation and immune system regulation.s amazing, simply transferring the microbiome in animals with mood disorders to a healthy animal is enough to make a difference and produce depression-like behavior in the latter," said one researcher.researchers found a number of bacterial species that were significantly reduced in animals with mood disorders. They then confirmed that oral treatment with the same bacteria could restore normal levels of lipid derivatives, thereby alleviating depression., these bacteria can be used as antidepressants. This treatment is called "psycho-biological therapy". findings show the role of the gut microbiome in normal brain function. If the gut bacteria community is unbalanced, some lipids that are vital to brain function disappear, creating depression-like behavior. In this particular case, the use of specific bacteria may be one way to restore a healthy microbiome and treat mood disorders more effectively. Compiled/Forward-Looking Economist APP Information Group original source: .