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Treat diabetes! CRISPR-edited cell replacement therapy enters the clinic

 Last Update: 2021-12-02
 Source: Internet
 Author: User

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On November 16, 2021, ViaCyte and CRISPR Therapeutics jointly announced that Health Canada has approved a clinical trial application (CTA) for CRISPR gene-edited stem cell-derived therapy VCTX210 for the treatment of type 1 diabetes (T1D)

The islet cells derived from the differentiation and expansion of stem cells in vitro will cause immune rejection, which will cause the body’s immune system to attack these cells and reduce the durability of the therapy

PEC Direct (VC-02), developed by ViaCyte, encapsulates the islet progenitor cells derived from stem cells in a "pocket" that can be implanted under the skin of the patient.

VCTX210 is derived from ViaCyte's pluripotent stem cell line CyT49

Reference materials:

[1] CRISPR Therapeutics and ViaCyte, Inc.

https://crisprtx.

(The original text has been deleted)

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