Under the new situation, how do Chinese medicine enterprises carry out drug innovation?

According to the data of [China Pharmaceutical network industry trends], in 2015, the market scale of Chinese traditional medicine was 391.8 billion yuan, accounting for 32.1% of the Chinese pharmaceutical market From 2011 to 2015, the compound growth rate of Chinese traditional medicine market scale was 16.8%, far higher than the growth rate of GDP The industry expects that from 2016 to 2020, the Chinese traditional medicine industry will continue to develop rapidly By 2020, the market size will reach 580.6 billion yuan, with a compound growth rate of 8.2% In 2020, the sales volume of traditional Chinese medicine market will account for 32.4% of the pharmaceutical market, basically the same as that in 2015 (under the new situation, how do Chinese medicine enterprises carry out drug innovation? However, with the frequent release of pharmaceutical policies, although some policies are favorable to the development of the Chinese medicine market, there are still great difficulties For example, homogenization is a very common problem for traditional Chinese medicine The upgrading of traditional Chinese medicine industry must rely on the elimination of enterprises with low technology level and small market scale If we do not carry out reasonable evidence-based research now, traditional Chinese medicine will face greater survival problems Therefore, traditional Chinese medicine enterprises need to carry out evidence-based research under the existing conditions In addition, although the market scale is huge, according to relevant statistics, the scale of traditional Chinese medicine industry is only one-third of chemical drugs, while the number of varieties is one-half of chemical drugs There is a lack of large varieties of traditional Chinese medicine, and the varieties only account for one twelfth of all varieties of traditional Chinese medicine In addition to varieties, there are also many dosage forms of traditional Chinese medicine, a total of 52 kinds, but from the common proportion, capsules, tablets, pills, granules, mixtures, etc account for a considerable proportion In terms of dosage form technology, traditional Chinese medicine is far behind chemical medicine Some insiders said that there is no big difference between the dosage form and dosage of traditional Chinese medicine two thousand years ago and that traditional Chinese medicine enterprises should develop and innovate while inheriting their ancestors' ideas and technologies Scholars believe that based on the rapid development of chemistry and life science and the increasing technical requirements of new drug evaluation of traditional Chinese medicine, traditional Chinese medicine enterprises and researchers can find and develop active compounds based on traditional Chinese medicine resources "The discovery of active lead compounds and innovative drugs from traditional Chinese medicine is still a rapid promotion with a high hit rate." The effective part of traditional Chinese medicine and its recurrence preparation can also be used as a breakthrough With the development of the basic research of traditional Chinese medicine and the modernization of traditional Chinese medicine, the effective components of traditional Chinese medicine have been clarified basically, the separation technology of traditional Chinese medicine components has been improved rapidly, and industrialization has been realized The separation and purification of effective components and effective parts of traditional Chinese Medicine has become a regular technology "It has become an inevitable trend for the development of modern Chinese medicine to separate and purify the effective parts or components, remove the ineffective, inefficient or toxic components, reduce the dosage and bid farewell to the black and large crude of Chinese medicine preparations." Some scholars said In addition, it is also a way to innovate traditional Chinese medicine on the basis of classic famous prescriptions The classic formula is a precious heritage left by the motherland to modern human beings, which has been inherited with its exact efficacy and high security It is not only the need of human health, but also a responsibility to inherit and innovate the classic prescriptions Traditional Chinese medicine enterprises can use modern science and technology to develop classic prescriptions and their addition and subtraction methods adjusted according to modern human diseases and living environment, which is also an important direction of new Chinese medicine research and development in the future It can also research and develop innovative drugs of famous and excellent Chinese patent medicines Traditional Chinese medicine enterprises can carry out systematic material basis and mechanism of action for famous and excellent Chinese patent medicines On this basis, famous and excellent Chinese patent medicines can be developed into modern traditional Chinese medicine with clear material and mechanism of action, advanced dosage form, small dosage and stable and controllable quality In this way, the R & D risk can be reduced and the market can be opened up easily With the strengthening of people's health awareness and the continuous promotion of China's big health industry, the traditional Chinese medicine industry will get more vigorous development But at present, there are many problems in the industry, especially in the innovation of traditional Chinese medicine.