Use exosome-based strategies to stop HIV in mice!

In a new study supported by the National Institutes of Health, researchers used exosomes, tiny nanoparticles that can be absorbed by cells to deliver new proteins to HIV infections.

"These results indicate that exosomal engineering has the potential to provide epigenetic-based treatments that can silence the expression of HIV genes in brain tissue, which is an area where HIV traditionally escapes HIV treatment

HIV attacks the immune system by infecting a type of white blood cell in the human body, and this white blood cell is essential for fighting infection

Researchers have been looking for a way to treat AIDS, this method is sometimes called "block and lock" method, especially for the AIDS virus in the brain

Dr.

When the researchers performed this exosome-based treatment on HIV-infected mice, they found that the protein delivered by the exosomes can silence HIV-infected cells.

"This exciting work shows that we can use exosomes to systematically deliver therapeutic payloads to HIV-infected cells

These findings indicate that exosomes can be used to transport proteins to HIV-infected cells in the body (including hard-to-reach brains) to inhibit HIV replication

Original search:

Shrivastava, S.