Viagra in Medicare? Behind the "blue lips" of Jinge is the difficulty of medication

Recently, academician Zhong Nanshan said at the Yangcheng International Forum on pulmonary hypertension (2019), "in the past decade, the discovery and application of targeted drugs have directly improved the clinical treatment of patients with pulmonary hypertension, but the price of imported targeted drugs is expensive, which has not entered the medical insurance in many areas, limiting their clinical application." From this point of view, he suggested that "Viagra" drugs enter the medical insurance Most patients are in the late stage when they are diagnosed Whether they can be found and treated early is an important research direction in the future As soon as the news came out, many people noticed that the role of Viagra is not only the "booster drug" we know in our daily life, but only the ED (erectile dysfunction) The reason can be traced back to the original birth story of Viagra The ingredient of Viagra is sildenafil Sildenafil was initially studied as a new heart disease drug, but in the process of use, researchers found that the drug has a significant effect on the impotence, so it was developed and marketed as a drug for the treatment of erectile dysfunction (ED) Why can Viagra treat pulmonary hypertension? The lung of human body is an important part of blood circulation To simplify, the blood in the body circulates in such a cycle: the venous blood with low oxygen content flows through the heart pump to the lung, through the pulmonary artery to the capillary network around the alveoli, carries out gas exchange with the alveoli, exhausts carbon dioxide, absorbs oxygen, becomes the arterial blood with high oxygen content, and then injects into the left atrium Such a circulatory process is called pulmonary circulation Pulmonary hypertension will destroy the smooth progress of this circulation When the pressure is too high, the pulmonary artery becomes narrow and the blood is difficult to circulate The result of inadequate pulmonary circulation is a decrease in blood oxygen content, which in turn causes blue lips and decreased endurance To solve the problem of pulmonary hypertension, the key is to find a way to relax the blood vessels Sildenafil is a kind of vasodilator Patients with pulmonary hypertension spend an average of 20000-200000 yuan on drugs every year, and they can't afford to take drugs, among which Viagra is relatively cheap Under the guidance of "the father of Viagra", the development of Viagra (sildenafil citrate tablets) has been well received by the public because the development of APIs and preparations follow the concept of "quality comes from design (QBD)", with good effect and favorable price According to a survey, more than half of patients with pulmonary hypertension are treated in sildenafil, so Zhong Nanshan is striving for Viagra drugs to enter the medical insurance In September this year, the video of Viagra, an 8-year-old girl, became popular on the Internet, which made the living conditions of patients with pulmonary hypertension appear With the help of caring enterprises, Xiaoya came to the First Affiliated Hospital of Guangzhou Medical University for treatment Academician Zhong Nanshan's team, which focuses on respiratory disease research, has made a special consultation for Xiaoya "As far as the current examination results are concerned, Xiaoya's condition is relatively complex, and serious pulmonary hypertension symptoms have occurred, requiring long-term medication." After consultation, Professor Liu Chunli, a member of the Zhongnanshan academician team of Guangzhou First Hospital of Medical Sciences, agreed that sildenafil was suitable for Xiaoya's current treatment In China, there are nearly 12 million people with pulmonary hypertension like Xiaoya (according to the statistics of China Charity Association) Without effective treatment, their median survival was only 2.8 years But at present, there are only twenty or thirty thousand people who really receive treatment Across the road of survival of this group, it is the difficulty of diagnosis, medication and expensive medication Zhong Nanshan said that for patients with pulmonary hypertension, because of early symptoms, only exercise ability and asthma, many patients go to hospital when they are serious; the cause is too complex, involving many specialist, general doctors are really difficult to diagnose; the incidence rate is not high, and the attention of medical staff is not enough, and the cognition of medical staff is not enough Therefore, the drug has the status of misdiagnosis and missed diagnosis Xiaoya's encounter is the epitome of the survival of patients Because of their inability to take high-priced imported drugs, many patients turn to cheaper generic drugs The data shows that at present, the targeted drugs for the treatment of pulmonary hypertension in the world are mainly divided into prostacyclin, endothelin receptor antagonists and type 5 phosphodiesterase inhibitors At present, there are 9 kinds of drugs on the market in China Research shows that long-term drug treatment can significantly improve the 5-year and 10-year survival rate of patients with pulmonary hypertension, but the drug cost of thousands or even tens of thousands of yuan per month makes many patients unbearable In the past 10 years, the discovery and application of targeted drugs have directly improved the clinical treatment of patients with pulmonary hypertension, but the price of imported targeted drugs is expensive, and they have not entered the medical insurance in many areas, limiting their clinical application A large number of studies and clinicians' prescriptions show that sildenafil can effectively relieve the symptoms of patients with pulmonary hypertension.