Viagra sells well, not necessarily men

Recently, Xiaoya, an 8-year-old girl from Xuchang, Henan Province, went to the drugstore alone to buy Viagra Her life span was extended by eating Viagra for 5 years, which attracted widespread attention Xiaoya ran to the drugstore and said that she wanted to buy "West Africa land" (commonly known as Viagra), and once she bought it, she would buy ten boxes, each box for 500 yuan In the past few years, such a slightly awkward scene has been staged In the face of other people's different eyes, Xiaoya's mother can only explain with tears again and again - her daughter is a patient with pulmonary hypertension, and taking Viagra can save her life At the Yangcheng International Forum on pulmonary hypertension held in Guangzhou on December 7, 2019, Zhong Nanshan, academician of the Chinese Academy of engineering, and a number of respiratory experts present affirmed this They said that from the perspective of the treatment of pulmonary hypertension, "Viagra" drugs into the medical insurance is imperative, one is really effective, the other is cheap Viagra is the original medicine of sildenafil citrate produced by Pfizer company Its approved indication is male erectile dysfunction, or ed for short For a long time, "Viagra" has been labeled as "Aphrodisiac" If it's the aphrodisiac that can't be included in the medical insurance naturally, few people know that Viagra's original intention is not to be aphrodisiac In fact, neither pulmonary hypertension nor ED is sildenafil's original mission "Viagra" was initially studied as a new heart disease drug, but in the course of use, it was found that the "Aphrodisiac" effect of the drug was relatively obvious, so it was developed and marketed as a drug for the treatment of erectile dysfunction In the past two years, Viagra found in actual use can treat pulmonary hypertension However, "Viagra" has not been approved in China for pulmonary hypertension Many companies have set up Viagra The first and most authentic Viagra produced by Jinge is Pfizer Due to patent protection, domestic enterprises are not allowed to produce imitation Viagra For a long time, Pfizer has dominated the huge domestic ED market All this continued until Pfizer's patent protection expired in 2014, and Chinese manufacturers finally came to the fore Viagra's generic drugs exploded in China in an instant Baiyunshan's generic drug "Jinge" is the first domestic Viagra, which was officially launched in the fourth quarter of 2014 It was in 2015 that the product was detonated At that time, the company named the online play "Prince and concubine promotion" The play became the "God play" of that year with a broadcast volume of 2.6 billion, which made Baiyunshan Jinge popular for a while Earn enough eyeballs at the same time, but also let more people know the existence of the Jango, the real start of the domestic "Viagra" cannon After Baiyunshan, many listed pharmaceutical companies have joined the competition in Viagra market At present, there are six enterprises that have obtained the production registration approval for sildenafil citrate tablets According to incomplete statistics, in addition to the "Jinge" produced by Baiyunshan, there are many domestic pharmaceutical enterprises in the layout of the beach, such as wanfile of Jiangsu Yabang Epson Pharmaceutical Co., Ltd., wanyeqiang of Changzhou Pharmaceutical Co., Ltd and other products have passed the application of "Viagra" generic drugs Photo source: Sina pharmaceutical's sales volume of Jinge exceeds that of Viagra Last year, maomei, a shareholder, reported that Changshan pharmaceutical called 140 million Chinese impotence According to its statistical data, "the number of domestic ED patients is about 140 million, assuming that 30% of them receive treatment, the number will reach 42 million Assuming that the treated ED patients can use drugs many times a year, the potential market size in China is expected to reach 10 billion yuan level in the future, with a broad market space." Although there are still doubts about the claim of "140 million patients", from Baiyunshan, the first domestic manufacturer of "Viagra", the market is not small According to Baiyunshan's 2018 annual report, Baiyunshan Jinge sold 47.74 million pieces in 2018, a year-on-year increase of 20.45%, and its operating revenue reached RMB 662 million, a year-on-year increase of 17.67% Since its listing, Jinge has contributed a lot of profits to the company Baiyunshan financial report shows that from 2014 to 2018, the operating revenue of Jinge was 56.3546 million yuan, 234 million yuan, 400 million yuan, 563 million yuan and 662 million yuan respectively, the operating costs of the same period were 4.7482 million yuan, 18.18 million yuan, 32.2227 million yuan, 41.4865 million yuan and 83.7454 million yuan respectively, and the gross profit margin was 91.57%, 92.31%, 92%, 92.54% and 87.31% respectively, with a total gross profit of 1.735 billion yuan In terms of sales volume, ginger leads the whole market According to the data of minenet, in 2016-2018, more than half of China's retail terminal sildenafil citrate tablets were sold by Jinge, accounting for 66.85% of the total sales in 2018, more than twice the sales of the original research product Viagra It is worth mentioning that according to the sales volume and revenue data of Jinge given by Baiyunshan, the gross profit margin of Jinge is more than 90% However, Baiyunshan did not explicitly disclose the gross profit rate data of Jinge in the annual report Such profiteering products also lead to the tearing up of shareholders due to the problem of interest distribution In July this year, kangyeyuan publicly reported that Baiyunshan had indirectly violated the interests of its partners According to Kang Yeyuan's complaint, in the past five years since its listing, Jinge has not received any revenue Kangyeyuan said that it holds 49% of the equity of Guangzhou Baiyunshan Pharmaceutical Technology Development Co., Ltd and 49% of the property right, operation right and income right of "domestic Viagra" - Jinge (sildenafil citrate) product As of the end of April 2016, Baiyunshan general factory had at least 400 million yuan of "Jinge" net profit, but kangyeyuan never obtained any profit Tianyancha shows that Baiyunshan and kangyeyuan are both shareholders of Baiyunshan Pharmaceutical Technology, with the former holding 51% and the latter 49% Kingo is one of the main products of the technology company Subsequently, Guangyao group issued a strict statement to the public, saying that the information involved in the report letter was seriously inconsistent with the facts, and that the company has reported the case to the public security organ and has been accepted It's too early to join the medical insurance Since the effect is good and the price is cheap, why is sildenafil not included in the treatment of pulmonary hypertension in China? There are also many difficulties behind this In fact, there are "formal instructions" for the treatment of pulmonary hypertension drugs included in the medical insurance On November 28, the State Health Insurance Bureau officially released the list of drugs that were successfully negotiated A number of drugs for the treatment of pulmonary hypertension have been shortlisted, such as Exelon's bosentan tablets, maxitan tablets and celepax tablets, as well as the leopard tablets jointly developed by mosadon and Bayer Bosentan tablets first entered the Chinese market in 2006, but his patent expired in October 2015 Like Viagra, there have been many generics since then At present, the domestic enterprises that have been imitated include Zhejiang Pharmaceutical, Zhejiang Huayi pharmaceutical, Jiangsu Yabang Johnson & Johnson pharmaceutical, Chongqing shenghuaxi pharmaceutical, Chongqing Huabang, Yuanda pharmaceutical, etc., all of which have been approved for clinical application In terms of price, some patients have disclosed that "in 2015, the price of bosentan for the treatment of pulmonary hypertension was 19980 yuan / box, about a month's dosage, while that of sildenafil was 495 yuan / box, about 2000 yuan / week There is a big difference between the two No wonder so many people choose Viagra." The high price of bosentan has not opened the market Since then, because a large number of generic drugs have entered the market, bosentan can only choose to reduce the price into the medical insurance According to the proportion of "average decrease of 60.7%" published by the National Health Insurance Bureau, the current bidding price of bosentan may be less than 5% of the highest But even with health care, "Viagra" is still much cheaper In addition, domestic generic drugs of sildenafil are relatively mature, so the cost of taking domestic "Viagra" generic drugs is lower The biggest obstacle in China is that sildenafil has not been approved for pulmonary hypertension in China It's like the Indian generic medicine in "I'm not the God of medicine" can cure people, but it's not allowed in China's law Although the medicine is not fake to save people, even if you know that Viagra can treat pulmonary hypertension, it is not officially recognized in China What's more, if doctors use this medicine to treat pulmonary hypertension, they may be suspected of using it "beyond instructions" There are many disputes on the legal level Once something happens, doctors need to take some legal risks In order to increase the indications, pharmaceutical and clinical research should be carried out in accordance with the drug registration management measures and relevant technical guidelines, and approved by the State Food and drug administration The clinical trial is very large, and the incidence rate of pulmonary hypertension is low Under the circumstance of uncertain profit, the motivation of pharmaceutical companies is not large First of all, we should popularize the knowledge of medicine, eliminate the worries and serve in silence According to the past data, Baiyunshan has publicized many times under the banner of "ginger can be used to treat patients with pulmonary hypertension" For example, since 2017, Jinge has launched the "blue lip new life program" love assistance program to provide assistance to patients with pulmonary hypertension, and that year was the beginning of Jinge's sales Zhong Nanshan has revealed that the incidence rate of pulmonary hypertension is 1%, and the number of such patients in China is 3-5 000 Although the coverage of ED patients is not as wide as that of ED patients, because these patients need to rely on drugs for long-term life, the frequency of consumption is 10 times or even 100 times higher than that of ED patients, so the dosage should not be underestimated So here comes the question Although Viagra is the drug, how much of it is sold to treat ed, and how much of it is used to treat pulmonary hypertension to protect life? On the other hand, if the scope of "Viagra" is opened, will bosentan and maxitan, who are specialized in the treatment of pulmonary hypertension, be willing? Therefore, all kinds of problems restrict Viagra's insurance Therefore, in the short term, the non generic companies of sildenafil may only serve the patients with pulmonary hypertension in silence Finally, cat sister thinks the first thing to do is to strengthen the popularization of related diseases and medicine knowledge, and the old concept needs to keep pace with the times To break this worry, the little sister who is not ed using Viagra doesn't have to worry about other people's strange vision to go into the drugstore and buy medicine.