We have 7 billion glass bottles between the new crown vaccine.

More than 100 teams around the world are racing to develop a new crown vaccine, and WHO revealed at a routine press conference on New Crown Pneumonia that there are more than 200 candidate vaccines worldwide, 15 of which are undergoing human clinical trialsthe bad news is that the lack of glass vials needed to store the vaccine makes it impossible to roll it out on a global scale immediately, even if it is approved for production"Even the vaccine bottles and filling procedures don't have enough reserves around the world, " said Gates, who was busy fighting the epidemic in the U.Sas early as late AprilOn June 16th,, the Wall Street Journal website again warned that a global glass shortage had emergedEven if the new crown vaccine is actually developed, it will not be shipped around the world in a timely and effective mannerthat is, the vaccine produces not enough bottles to be used by those who need it"There are only 200 million vaccine glass bottles left in the world," John Bell, a professor at Oxford University's School of Medicine, told the BBC on April 30,Jeremy Farrar, chairman of the Wellcome Trust, agrees: "There is now a crisis of glass bottle shortages"
also need to be made clear that these 200 million vaccine bottles, but not all of the new crown vaccine, but also to protect the availability of influenza, typhoid and meningitis vaccinesworse, the production chain of vaccine bottles has also been affected by the impact of the outbreakshortage of vaccine bottles means that even if the new crown vaccine is successfully developed, billions more people around the world will struggle to get vaccinatedthe production of that vaccine bottle can keep up with the pace of vaccine development?the world's top four vaccine manufacturers - GlaxoSmithKline, Merck, Sanofi and Pfizer - produce nearly 90 percent of the world's vaccinesasked about the small glass bottles, GlaxoSmithKline responded with "decentness": "Given the needs of the present and the future, we will continue to work closely with suppliers, including glass bottle suppliers""Production tasks are difficult to solve, " says Vijay Samantha, a former head of vaccine manufacturing at theMerck GroupThinking about this, I can't sleep at night."and with current research, people may need to be vaccinated more than once against the new coronavirus to increase their immunity to the new coronavirusthat means maybe a person needs a lot of vaccine bottled vaccines, there are 7.59 billion people in the world, how many glass bottles? Pacific Securities' pharmaceutical research team gave us a bill:source of data: Pacific Securitiesthe best immune effect of several doses of vaccines, and how much penetration the vaccine can have is unknown50% penetration and two injections, more than 7 billion glass bottles will be used, and now if there are only 200 million in the world for other vaccines, the gap is a bit large, a former director of the Us Department of Biomedical Research and Development, who was recently removed from his post, announced on May 5 thinly ill-gotten warning of a "serious shortage" of glass vials used by the US Department of Health to fill vaccines and that "it could take up to two years to produce enough vials to meet Us vaccine demand." "
vaccine has not arrived, but the container has become a "bottleneck."medicinal glass, not as good as a beer bottleglass itself is not very inert, drugs and glass long-term contact, alkali metal ions will occur, arsenic, palladium, aluminum ions will be released into the liquid, arsenic, radon as toxic heavy ions, and aluminum ions are an important cause of Alzheimer's disease, the vaccine is not a common liquid, in a glass bottle, there are several basic requirements, such as clean and hygienic, low temperature resistance, wear resistance, good air tightness, can not produce chemical reactionsAmong them, can not produce chemical reactions, the most criticalVaccines are chemical agents that, in the event of a chemical reaction with a glass bottle, can be contaminated and pose a safety hazardthis requires looking at the water resistance of the glass: the higher the water resistance , the less the risk of reacting with the drug, the better the quality of the glass bottle according to the water resistance from low to high, medicinal glass can be divided into: sodium calcium glass, low boron silicon glass and medium boron silicon glass what glass should the bottle for the vaccine be made to be safe? this kind of glass has a better chemical stability, alumina content is low, water- and acid resistance is excellent, the drug has a very good protective effect, with the long-term contact with the liquid will not cause changes in the ph value, there will be no precipitated or glass chip fall off (such glass is called neutral glass), this kind of glass is also known internationally as class I bottle there are many factors affecting glass performance , one of which is the content of boron trioxide, content of 8.0-12.0 (m/m) for medium boron glass, content of 12.0 (m/m) for high boron glass, medium boron and high boron glass are well in line with the requirements of neutral glass the international market, especially in Europe and the United States, injections, including injection, blood and blood preparations, etc., in principle, are using Class I glass, that is, the daily common vaccine and other water needles injections in accordance with international standards should use Class I glass in response to the shortage of vaccine bottles, May 18, China Vaccine Industry Association official WeChat revealed that in response to some recent media reports that "vaccine bottle shortage will affect vaccine production", China Vaccine Industry Association based on vaccine bottle industry observation and industry data, in communication with several benchmark enterprises after communication and demonstration, China has a high-quality vaccine bottle production industry base, according to incomplete statistics, annual output of at least 8 billion, to meet the demand for new vaccine production most of China's medium boron silicon glass depends on imports, why can it produce 8 billion vaccine bottles? The reason for is simple: the shortage of vaccine bottles worldwide is not the same as the 8 billion vaccine bottles that China can produce to be more direct, China's vaccine bottle, the material used is not medium boron silicon glass statistics show that more than 90% of China's medicinal glass bottles are still using low-boron silicon glass in China, the annual demand for medium boron silicon glass is about 50,000 tons, but the yield is only 7% to 8% China's pharmaceutical glass packaging in-depth research and investment strategy report (2019) shows that China's medicinal glass products are mainly low boron silicon glass and sodium calcium glass the main reason of is that for china's medicinal glass production enterprises, the cost of medium boron silicon glass is higher, and secondly, the production stability of the medium boron glass tube is difficult to control cruel reality is that the underdeveloped level of pharmaceutical packaging is an open secret in the pharmaceutical industry China's annual production of biological agents, vaccines and other types of injections in the scale of more than 30 billion, but the domestic production of relatively in line with international standards of Class I bottles of the size of only 3 billion or so, a large number of domestic pharmaceutical companies are using low boron glass (can not meet the requirements of neutral glass) and sodium calcium glass low-boron glass for China's specific historical development of the product, in the 1960s, the domestic pharmaceutical industry developed rapidly, domestic enterprises developed and produced can basically meet the requirements of drug use at that time low boron silicon glass (boron trioxide content 5-8% (m/m) low-boron glass loading after a period of time will produce crystal destruct, the alkali metal out of a higher amount, anti-hot and cold impact performance is poor will also affect the effect of the drug, it can be said that low boron glass can only be a neutral boron silicon glass degradation grade, quality and performance of the alternative as mentioned above, compared with medium boron silicon glass, the stability of low boron silicon glass is much worse if the new crown vaccine is installed in a low-boron silicon glass bottle, there may be a chemical reaction that contaminates the vaccine that doesn't have to be a rescue Europe and the United States has mandated the use of neutral boron silicon pharmaceutical glass as a packaging material for all injectables, blood and blood preparations (biological agents) China has no such requirements in the past, resulting in slow growth in domestic demand, domestic neutral boron silicon glass market marketing is difficult But at present, China already has the technology of producing boron silicon glass, has the conditions for large-scale localization, and China can afford the cost of boron silicon glass in the short term, the domestic vaccine glass bottle technology upgrade will take time, the use of ordinary low boron silicon glass proportion will be very large it's time to enforce medium boron silicon glass China's new crown vaccine research and development in the forefront of the world, should not be dragged by the district glass bottle.