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Freeze-drying machine is a small in-situ freeze-drying equipment, which is suitable for pilot workshops of pharmaceutical factories and small-scale production use.
It can also be used for food and freeze-drying treatment.
It eliminates the pollution caused by the material transfer process and realizes the automation of drying and sublimation.
The pilot-scale freeze dryer has shelf heating and programming functions, and can memorize the freeze-drying curve, which is convenient for users to explore the production freeze-drying process
.
The products are divided into standard type and gland type, which are widely used in pharmaceutical factories and food factories
.
Advantages: There are various drying methods, such as sun drying, boiling drying, drying, spray drying and vacuum drying, etc.
, but common drying methods are usually carried out at temperatures above 0 °C or higher
.
The products obtained by drying generally have the problems of reduced volume and hard texture, most of the volatile components will be lost, some heat-sensitive substances will be denatured and inactivated, and some substances may even be oxidized
.
Therefore, the dried product has a great difference in properties compared with that before drying
.
The freeze-drying method is basically carried out below 0 °C, that is, in the state of freezing the product, and generally does not exceed 60 °C during analytical drying
.
Under vacuum conditions, when the water vapor sublimates directly, it remains in the frozen ice shelf, forming a sponge-like loose porous structure, so its volume is almost unchanged after drying
.
Before re-use, just add water for injection and it will dissolve immediately
.
Disadvantages: As the so-called technology that does not exist, the main disadvantage of vacuum freeze-drying technology is the high cost
.
Because it needs vacuum and low temperature conditions, the vacuum freeze dryer needs to be equipped with a vacuum system and a low temperature system, so the investment cost and operating cost are relatively high
.
It can also be used for food and freeze-drying treatment.
It eliminates the pollution caused by the material transfer process and realizes the automation of drying and sublimation.
The pilot-scale freeze dryer has shelf heating and programming functions, and can memorize the freeze-drying curve, which is convenient for users to explore the production freeze-drying process
.
The products are divided into standard type and gland type, which are widely used in pharmaceutical factories and food factories
.
Advantages: There are various drying methods, such as sun drying, boiling drying, drying, spray drying and vacuum drying, etc.
, but common drying methods are usually carried out at temperatures above 0 °C or higher
.
The products obtained by drying generally have the problems of reduced volume and hard texture, most of the volatile components will be lost, some heat-sensitive substances will be denatured and inactivated, and some substances may even be oxidized
.
Therefore, the dried product has a great difference in properties compared with that before drying
.
The freeze-drying method is basically carried out below 0 °C, that is, in the state of freezing the product, and generally does not exceed 60 °C during analytical drying
.
Under vacuum conditions, when the water vapor sublimates directly, it remains in the frozen ice shelf, forming a sponge-like loose porous structure, so its volume is almost unchanged after drying
.
Before re-use, just add water for injection and it will dissolve immediately
.
Disadvantages: As the so-called technology that does not exist, the main disadvantage of vacuum freeze-drying technology is the high cost
.
Because it needs vacuum and low temperature conditions, the vacuum freeze dryer needs to be equipped with a vacuum system and a low temperature system, so the investment cost and operating cost are relatively high
.
