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    Home > Biochemistry News > Biotechnology News > What bad habits do dads have that affect your child's health? What is the impact?

    What bad habits do dads have that affect your child's health? What is the impact?

    • Last Update: 2020-08-07
    • Source: Internet
    • Author: User
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    Many of the father's habits and lifestyles affect children' conditions, such as age, stress, and diet, all of which are associated with the health, behavior, and even the risk of certain diseases.
    now, two mouse-based studies have revealed that fatherexercise, smoking or not, can affect sperm quality, and in turn affect the health of the next generation and the next generation.
    . Non-exercising Dads: The Risk of Obesity and Diabetes for Offspring, Professor Kristin Stanford and the team based on mouse models, found that the amount of exercise a father has before pregnancy can have a lasting effect on a child's metabolic health.
    male mice that exercised were more likely to produce healthy offspring than non-exercising male mice.
    whether the results will be applicable to humans is uncertain, scientists support the idea that "exercise is good for future generations."
    research published in the journal Diabetes under the title "Paternal Exercise Improves Glucose E. E. E. E. E.
    the mice were fed high-fat foods for three weeks, and the mice were divided into two groups: a group of mice were placed in a device with wheels, running an average of nearly 6 kilometers a night.
    the other group of mice were in the "couch potato" type.
    they will dissect some mice that have obtained sperm samples, and the remaining mice will have the next generation with normal female mice.
    the researchers followed the mice until the age of one (equivalent to middle-aged mice).
    found that offspring of male mice showed better ability to control blood sugar and lower levels of insulin, which meant they had good metabolic ability.
    , incontrast, mice born to inactive obese male mice contained more fat and were poorly tolerated glucose.
    further analysis of sperm cells in male mice, and the researchers found that the sperm of lazy dads contained trans-RNA fragments.
    these molecules (full- and complete) are important for protein synthesis, it remains a mystery how fragmented RNAs work, and some scholars speculate that they may affect protein production.
    by contrast, the sperm of the father who insisted on exercising contained fewer RNA fragments.
    Kristin Stanford's team doesn't know how RNA fragments affect the metabolism of offspring.
    they speculated that some of the debris could alter the growth and development of the embryo early in pregnancy.
    and, by following the mice for a year, the researchers predicted that the effect could "cover the life of future generations."
    the most interesting thing about this study is that the high-fat diet of dads affects the metabolism of offspring, but exercise can counteract the effects -- when male mice exercise, their offspring's metabolism improves in adulthood, even if they still eat high-fat foods.
    "obesity in adult males can affect sperm count, quality, and even reduce the rate of suspected conception."
    Now this study is a reminder that exercise may change the impact.
    ," the researchers explained.
    . Smoking Dads: Linked to next generation, next generation health in another study, the focus is on "nicotine", that is, smoking.
    previous studies have shown that smoking in pregnant women increases the risk of behavioural disorders in their offspring.
    but in fact, smoking is far more common among men than among women.
    , scientists from florida State University School of Medicine found that exposure to nicotine in men can lead to cognitive impairments in their children and grandchildren.
    the study was published in the journal PLOS Biology under the title "Nicotine exposure of the male mice mice produces the life of the changes of the generation of the generation of the generation of the sons."
    team also modeled mice by adding nicotine to the drinking water of male mice. After 12 weeks of feeding
    , the mice were "breeding" with female mice, and the mice they gave birth to (F1 generation) gave birth to F2 with the other half who were not exposed to nicotine.
    found that both male and female, F1 mice showed defects in spontaneous motor and inverse learning.
    , male offspring also showed significant deficiencies in attention, monoamine content in the brain, and dopamine receptor mRNA expression.
    , although the apparent hyperactivity and attention deficit performance carried by The F1 mice was not inherited to the F2 generation, the male F2 generation mice showed defects in reverse learning.
    " In analyzing sperm from fathers, we found epigenetic changes in multiple genes.
    " explained the author of the paper, Deirdre MCarthy, a researcher at Florida State University School of Medicine.
    in particular, the promoter DNA methylation of the dopamine D2 receptor gene has changed.
    the receptor plays a key role in neurodevelopment.
    researchers speculate that this may be the source of cognitive impairment in future generations.
    in all, the presence of nicotine can lead to epigenetic changes in sperm cell genes, which are likely to affect key neurodevelopmental pathways in future generations, leading to ADHD, attention deficit, and cognitive problems (typical symptoms of ADHD, autism spectrum disorder in humans).
    even, grandchildren will experience learning disabilities as a result of this.
    suggests that some of the harmful effects associated with nicotine can be passed down from generation to generation.
    note, only some obvious F1 defects are passed on to F2 male mice.
    this means that at least some of the harmful effects of nicotine exposure may be temporary.
    researchers believe the results could be extrapolated into humans.
    " these data suggest that some children and adults may have cognitive impairments that can be traced back to the previous generation and the previous generation. "In the 1940s, 50s and 60s, smoking was more common and more acceptable than it was now," said Pradeep Bhide, a professor of neuroscience at Florida State University School of Medicine at the
    .
    "Source:Biological Exploration.
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