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    Home > Biochemistry News > Biotechnology News > Where does the new crown virus come from and from? The source of the new coronavirus should be given accurate answers by scientists.

    Where does the new crown virus come from and from? The source of the new coronavirus should be given accurate answers by scientists.

    • Last Update: 2020-08-04
    • Source: Internet
    • Author: User
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    World Health Organization (WHO) Director-General Dr. Tan Desai warned at a press conference in Geneva on April 20that a lack of unity is fuelling the outbreak of new crown pneumonia.
    he called for "not to use the virus as an opportunity to confront each other or win political points."
    it's dangerous, like playing with fire.
    " he warned that "the worst is yet to come" if solidarity is not strengthened within and between countries.
    throughout the history of human development, the virus has been with it and never left.
    Despite the increasing level of human technology, we sometimes have nothing to do with the virus.
    the new crown pneumonia outbreak to ferocious, its rapid spread, widespread spread, far-reaching impact, a hundred years rare. Where
    the new crown virus comes from and where does it come from? How has it evolved? Everyone wants an answer.
    this answer, although we will not get it in a short time, but I believe that one day will be the world. It is common knowledge that
    the profession has specialized skills, and scientific problems ultimately need to be solved by scientists.
    that's why the White House Office of Science and Technology Policy sent a letter to the National Academy of Science, Engineering and Medical Sciences (NASEM) in early February asking for scientists' advice on issues related to the new coronavirus tracing study.
    also appears the phenomenon of viral retroactive politicization, because it is difficult for people to wake up.
    trace the new crown virus, and the responsibility of the scientist community is not to be left to rest.
    but scientists are not omnipotous, because virus tracing research is not a work of the future.
    Dr. Yuqi Zhao, a member of the American Academy of Microbiology and a virologist at the University of Maryland, said that viral tracing research is a scientific problem and has a lot of uncertainty.
    scientists need to go through epidemiological investigation, genomic analysis, host (intermediate and natural host) screening identification, field sampling, homologous research on virus isolates, and finally bioinformatics analysis certification to trace the source of the virus.
    it can be seen that virus tracing research is a time-consuming and labor-intensive long-term process, should give scientists sufficient research time.
    there are many scientists around the world who are currently conducting scientific research on the new coronavirus, and trace-and-source research is naturally one of the key points.
    but so far, the tracing of the new coronavirus is only in its early stages.
    the March 17 issue of the journal Nature Medicine, the United States, Britain, Australia, six scientists in the study paper, can be called "heavy" results.
    they point out in their paper that the new coronavirus cannot have been created in the laboratory, but rather a natural evolution, possibly a natural choice of the virus for human or animal hosts.
    know that not only are the six scientists, not only the world-famous "virus hunter" and Columbia University professor Ian Lipkin, but also The NaSEM at the request of the White House, the newly established "emerging infectious diseases and 21st century health threats" member, the United States Scripps Institute microbiologist Christian Anderson, they are an authority in the academic community, their current research on the origin of the virus is worthy of great attention.
    however, from a scientific point of view, the new crown virus tracing research is still a long way to go, and now the new crown virus traceability research results into the public view are still far from the real scientific answer.
    with the global epidemic becoming more serious, scientific and decisive measures to prevent and control the epidemic is essential.
    using the virus and the epidemic as a political tool would not only not help prevent and control the outbreak, but would also be counterproductive and have more serious consequences.
    that is why many scientists around the world are calling for a scientific approach to the outbreak, to promote scientific argumentation, and to promote international cooperation.
    cooperation among countries, especially among scientists, is even more valuable at a time when many of the world's normal scientific research activities have been severely affected by the outbreak.
    As NASEM said in a letter to the White House Office of Science and Technology Policy, international scientific cooperation is more important than ever to address research issues such as virus tracing and overcome the global challenges posed by the new coronapneumonia outbreak.
    Related News: Virus tracing should be the global "joint operation" - an exclusive interview with The National Nagasaki University of Japan virologist Bei lihaixiong Xinguan pneumonia outbreak has occurred more than 3 months, ravaged more than 200 countries and regions around the world, the number of infections is increasing.
    , Nord-Ari, a virologist at Japan's National Nagasaki University, is worried about the situation. In an interview with Science and Technology Daily,
    made a detailed analysis of the characteristics of virus transmission, the scientific and long-term nature of virus tracing, and the contribution of Chinese scientists, and called on the world to "jointly fight."
    the characteristics of the spread of the new coronavirus and the main cause of the global pandemic, the summary of the global epidemic, combined with many studies around the world, compared with the previously found SARS-CoV and MERS-CoV, this time the new coronavirus has several new and significant characteristics.
    first, the neo-coronavirus's stingprotein (S protein) is the protein responsible for the viral particles and their infected cells, the surface receptor senile tension in the human angiotensin conversion enzyme 2 (ACE2), and the s protein of the new coronavirus binds to its cell receptor ACE2 with a affinity force 10 to 20 times higher than the SARS-CoV S protein.
    the high affinity of S protein-receptor binding showed that viral particles adhere strongly to cells and are prone to infection of cells.
    the infection process of infecting infected cells, like respiratory-infected veto viruses such as influenza viruses, has the characteristics of protease dependence.
    S protein itself is the precursor protein no cell fusion activity, only by the cell's protease cut into S1 and S2 two protein fragments, S2 is responsible for cell membrane fusion fusion peptide (FP) exposed, S protein is activated, viral particles can be integrated with the infected cell membrane fusion, intrusion into the cell, complete its infection process.
    the second characteristic of the new coronavirus is that its S protein has SARS-CoV and MERS-CoV's S protein does not have, S1 and S2 there is a Furin protease enzyme cut point.
    Furin protease is a common protease in human cells.
    newly crowned virus particles are assembled and released from infected human cells, the virus S protein has been cut into the activated state of S1 and S2 by Furin protease in the cells, and its virus particles already have strong cell infection and membrane activity, a characteristic that makes the infection efficiency of the new coronavirus may be nearly 1000 times higher than SARS-CoV infection.
    finally, the structural characteristics of the new coronavirus S protein determine its strong infection of cells and rapid replication ability.
    , therefore, infected people have not yet developed systemic symptoms of the initial release of a large number of highly infectious virus particles.
    more infectious than the flu virus is the main reason why the new coronavirus can be a worldwide pandemic.
    virus tracing is a very serious scientific issue, need to have clear evidence to support the Northern Said, coronavirus can be classified as alpha, beta, gamma, gamma 4 genus.
    , radon is the main infected birds, while alpha, beta is the main infection of mammals, the new coronavirus classification belongs to the beta genus, natural host may come from bats, there are also reports in pangolins, snakes and other wild animals found similar viruses.
    the true route of transmission of the new coronavirus from a natural host or through some intermediate host infects a person, or a person directly infected.
    therefore, the virus tracing, looking for intermediate host, studying the transmission of the virus into the population, for the complete cut-off of the spread of the virus, is of great significance.
    this is a very serious scientific issue, and since it is science, there needs clear evidence to support it.
    solve d'etre, it will require the joint efforts of scientists from all over the world.
    screening of suspected influenza cases, serum antibodies may provide clues to the search for a source, and the history of the plague, which has been on the rise, bodes well for new viruses that are invading populations from other organisms.
    the emergence of each new type of virus, because the human body does not have natural immunity to it, so the immune system can not effectively prevent the infection of the virus, the virus will continue to spread in the population to replicate its "children", until the majority of the population has immunity to it, in order to curb the development of the epidemic.
    the most effective way for humans to deal with emerging virus infections is to research and develop vaccines, and before they are successfully developed and vaccinated for mass immunization, everyone is susceptible to the virus and it is difficult to be alone.
    the body's immune system has a memory function for infections that invade pathogens in the body.
    use current technology to detect antibodies in the blood and screen for the "cv" of a variety of pathogens that have been infected.
    if serum antibodies are widely screened in patients with clinically suspected influenza cases worldwide in the future, it could help provide clues in the search for the source of the new coronavirus infection.
    Chinese scientists to meet the new challenge has stood up for the first shift this new crown virus pneumonia outbreak although Wuhan was the earliest reported, but the source of the virus has not been finalized in the science.
    in the early stages of the outbreak, Chinese doctors and scientists used the shortest time to efficiently isolate the virus, parse the whole genome of the virus, and quickly open to the world, so that the world quickly recognized the emergence of a new type of coronavirus infection.
    this fully reflects the excellent Chinese scientists and the responsible spirit of the cause of human public health, for mankind to face new challenges together to stand the first shift.
    in addition, in order to quickly control the spread of the epidemic, the Chinese government at the expense of the economy suffered major losses, quickly adopted the history of mankind is unique, the size of more than 10 million people to implement strict urban closure measures, so that the spread of the epidemic in the country has been effectively curbed.
    China's efforts and sacrifices have won valuable time for the world to jointly confront the epidemic, which has been highly appreciated and evaluated by the International Health Organization and relevant experts from various countries.
    the spread of the worldwide epidemic, countries should "jointly combat" when the outbreak occurred in China in the early stages, the world should be immediately alert, to be prepared for all kinds of response.
    it is regrettable that there are many countries where some biased and irresponsible politicians are unable to take the right and positive defensive measures to effectively stem the spread of the epidemic in their countries, leading to its spread throughout the world. in order to shirk their political responsibilities,
    , they have used media hype to cast a political and ideological shadow over what is supposed to be a "joint operation" of humanity against a common enemy.
    Beili said that the outbreak of new crown pneumonia is a once-in-a-century global public health crisis, not only a serious threat to human life and health, the political, economic, national management system of human society and other systems also brought great challenges.
    virus poses a great threat to human life and health, and its violations never divide the country, race, sex, age and social status, and are the common enemies of mankind.
    in the face of the common enemy of mankind, all countries of the world should unite, pool the wisdom and scientific and technological strength of mankind, and join hands in the fight against it.
    Beili reminded that the new coronavirus may flare up again at any time before the widespread vaccination of humans, without affecting the normal social stability and development, should actively do a good job of all kinds of records.
    EU: Creating a new crown pneumonia data sharing platform, according to the European Commission's official website reported on the 20th, the European Commission and several major partners, launched the "Europe's new crown pneumonia data platform", which is the European Union to support European and global researchers to combat the new crown pneumonia, the aim of quickly collecting and sharing available research data to better respond to the outbreak. "Now researchers must stand together and fight against each other to better understand and respond to the common enemy of the new crown virus," said Maria Gabriel, the European Commission's Commissioner for Innovation, Research, Culture, Education and Youth,
    .
    " the platform is the result of joint efforts by the European Commission, the European Institute of Bioinformatics (EMBL-EBI), the European Alliance for Big Data in Life Sciences (Elixir) and the COMPARE project, as well as EU member states.
    it is understood that the new platform will provide an open, reliable and scalable European and global environment in which researchers can store and share data sets such as data related to dna sequences, protein structures, preclinical and clinical trials, and epidemiological data.
    the European Commission says fast and open data sharing will greatly accelerate research and development and allow researchers to respond more efficiently to the new coronavirus.
    the European New Crown Pneumonia Data Platform is in line with the principles established in the European Statement on Data Sharing in Public Health Emergencies, which emphasizes open research data to address social challenges more efficiently and reliably.
    the platform is also a pilot project aimed at achieving the goal of the European Open Science Cloud (EOSC).
    the European Commission said the platform was part of the European Research Regional Action Plan for the Response to the New Crown Virus (ERAvs Corona).
    April 7, 2020, the Ministers of Research and Innovation of all EU member states jointly launched the "ERAvsCorona Action Plan" 10 priority actions to strengthen close collaboration, cooperation, data sharing and co-financing between the EU and member states to help researchers and EU member states better respond to the new crown outbreak.
    in addition to the "European New Crown Pneumonia Data Platform" launched today. Other initiatives proposed by
    ERAvsCorona include coordinating funding, expanding large-scale clinical trials across the EU, and increasing support for innovative companies.
    in the coming months, the European Commission will work with member states to update priority actions and take appropriate measures.
    the European Commission said the EUROPEAN Union was taking strong measures to tackle the new coronal pneumonia, and the EU has pledged hundreds of millions of euros to speed up the development of new coronavirus vaccines, new therapies, diagnostic tests and medical systems to prevent further transmission of the coronavirus.
    the European Commission has funded EUR 48.2 million for 18 research projects from 151 research teams around the world to develop immediate diagnostic tests, new therapies, new vaccines and epidemiological models to improve the ability to cope with neo-glyceme.
    the European Union has also provided financial support of 80 million euros to an innovative company to expand the development of the coronavirus vaccine.
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