Why can domestic dogs adapt to the European milk diet?

Why can domestic dogs adapt to the European milk diet? Research reveals genetic mechanism

Why can domestic dogs adapt to the European milk diet? Research reveals the genetic mechanism why domestic dogs can adapt to the European milk diet? Research reveals genetic mechanism

BEIJING, Kunming, July 31 (Reporter Hu voyage) 31 reporters from Zhong Keyuan Kunming Institute of Zoology, was informed that the Zhang Yaping Academy of Sciences research group, researcher Wang Guodong Liang Bin, a researcher and research group research group composed of Yunnan University, a joint research team , Revealing for the first time the genetic mechanism of domestic dogs adapting to the European milk diet
.

Related research results were recently published in Molecular Biology and Evolution, a well-known journal in the field of evolutionary biology

Zhong ASTRI ASTRI Zhang Yaping Academy of Sciences

Domestic dogs were domesticated from gray wolves in Eurasia about 15,000 to 40,000 years ago, and they have now spread throughout most of the world's places where humans live
.

Domestic dogs and humans live in the same environment, and there are convergent evolutions in many aspects

The joint research team used the genome data of 242 European breed dogs, 38 Southeast Asian domestic dogs, and 41 gray wolves.
Genome-wide selection signal scanning revealed that LCT, a gene encoding lactase, is strongly positively selected in European domestic dogs.
Medium lactase tolerance is related to milk eating habits
.

Further analysis showed that the frequency of the A-to-G mutation at positions 38,609,592 on chromosome 19 of domestic dogs was nearly fixed in European domestic dogs and Middle Eastern domestic dogs, at 91.

At the same time, the joint research team used the published 737 canine animal genome data to analyze the distribution of the mutation in domestic dogs in Asia, Europe and Africa
.

The results show that its distribution trend in different regions is similar to the human lactase tolerance phenotype, implying the convergent evolution of domestic dogs and humans in the milk diet

The research was supported by the National Natural Foundation Youth Project, Yunnan Province, scientific and technological innovation team, the state's key R & D programs and China Kexue Yuan funding cutting-edge science research projects, the International Federation of dog genome is another important achievement
.

(Finish)

Academy of Sciences