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WuXi Ju Norici Orenza Injection Approved for Second-Line Treatment of LBCL

 Last Update: 2022-05-26
 Source: Internet
 Author: User

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On March 31, WuXi Junuo announced that its CD19-targeting autologous chimeric antigen receptor T (CAR-T) cell immunotherapy product, Benoda® (Rigiorenza Injection), is used in the second-line treatment of large The pivotal clinical trial application for B-cell lymphoma has been granted implicit approval by the National Medical Products Administration (NMPA) of China

B-cell lymphomas are a heterogeneous group of tumors with monoclonal expansion of malignant B-cells, accounting for approximately 85% of non-Hodgkin lymphomas (NHLs)

The approved study is a multi-center, randomized, controlled, open-label Phase III clinical study in China, aiming to use first-line drugs (anthracyclines and rituximab or other CD20-targeted drugs) To evaluate the efficacy and safety of Benoda® in adult subjects with r/r LBCL who did not achieve a CR after treatment, or who relapsed within 12 months of CR

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