Xiao Zeyu's research group from the School of Basic Medicine designed DNA self-assembly "nano dandelion" to achieve photothermal therapy...

Recently, the research group of Professor Xiao Zeyu from the School of Basic Medicine published a research result entitled "DNA-assembled visible nanodandelions with explosive hydrogen-bond breakage achieving uniform intra-tumor distribution (UITD)-guided photothermal therapy" in Biomaterials, a well-known journal in the field of biomaterials.

Tumor photothermal therapy is a treatment method in which photothermal agents are concentrated in tumor tissue and triggered by near-infrared light (NIR) irradiation, which converts light energy into heat energy to kill cancer cells

In response to this important medical issue, the researchers were inspired by the scattered seeds of dandelion, and prepared a dandelion-like structure of DNA self-assembly visualization nanomedicine, named DNA self-assembly nanodandelion (GRS-DNA-CuS)

Zhang Yongming, a doctoral student at Shanghai Jiao Tong University School of Basic Medicine, assistant researcher Cui Yanna and master student Li Mingwang are the co-first authors of the paper