Yang Sheng's research group discovers highly active CRISPR transposase for orthogonal multiple editing

On September 3, 2021, the international academic journal Nucleic Acids Research published online a research paper entitled "Orthogonal CRISPR-associated transposases for parallel and multiplexed chromosomal integration" completed by the Yang Sheng research group of the Center for Excellence in Molecular Plant Science, Chinese Academy of Sciences

Designing and debugging a microbial cell factory often requires interrupting a batch of genes and/or debugging the optimal dose ratio of a batch of genes

This study further unearthed the seventh type of CAST derived from Pseudoalteromonas translucida KMM520 (Pseudoalteromonas translucida KMM520), called PtrCAST

Researcher Yang Sheng from the Center for Excellence in Molecular Plant Science of the Chinese Academy of Sciences is the corresponding author of this study.

Link to the paper: https://academic.

Left: Comparison of the efficiency of 7 CRISPR-related transposases.