Ye Kai: Excavation of the medicinal value and biological information coding of opium poppies.

Since the poppy is the main raw material for opium production, it is often referred to as the "flower of evil".
", "But people may not know that poppy also has medicinal value, and its extract is also an important ingredient in a variety of sedatives. Ye Kai, a professor at Xi'an Jiaotong University's School of Electronics and Information Engineering at
, told Science and Technology Daily that he wanted to show the other side of the "flower of evil".
, the ye Kai team, the University of York professor Ian Graham's team, and the Wellcome Foundation Sanger Research Fellow Ning Zemin's academic paper, "The Opium Poppy Genome and the Synthesis of Morphine Mink" published in the journal Science, published for the first time the results of the high-quality whole genome sequence and assembly of opium poppy.
this achievement provides an important foundation for further exploration of the medicinal value of opium poppy and for revealing the evolutionary history of poppy and even early gemini plants.
cross-border research, from biological experiments to information coding, although today Ye Kai has been rooted in the field of bioinformatics for many years, but it is not interdisciplinary scholars at the beginning.
while studying, Ye Kai moved into the field of biology, where he spent most of his time doing biological experiments.
a single biological experiment that could hardly satisfy Ye Kai's curiosity, he focused on a new field, bioinformatics.
it wasn't until 2004 that He went to Leiden University to study the interdisciplinary subject of bio-information.
since then, abstracting biological processes into information has become Ye Kai's main task.
twisted DNA double helix, mysterious supergene clusters... At that time, Ye Kai had to deal with them every day.
in order to learn as soon as possible, master the knowledge of this cross-discipline, Ye Kai very desperately, stay up late to check the data, do experiments become his daily.
's hard work has finally paid off: since 2008, he has developed a series of genomic sequencing data analysis solutions and published 53 SCI papers.
this makes Ye Kai an early international exposure to second-generation high-throughput sequencing technology and data, and he is also a key member of major international scientific projects such as the U.S. Cancer Genome Map.
since 2008, Ye Kai has tried to apply bioinformatics technology to precision medicine.
Ye Kai has developed a series of genetic mutation detection methods and analysis systems, some of which, such as Pindel testing system, has been developed as one of the core detection methods in this field, has been widely used by multinational scientific research units, medical institutions.
March 2016, Ye Kai came to Xi'an Jiaotong University, which in April of the same year set up a "Ye Kai Young Scientist Seoun Studio" with distinctive interdisciplinary features, encouraging him to continue his cross-cutting research work in many fields, such as big data mining, algorithm design, cell engineering, genomics, etc.
team, cultivate members of the international vision Although the current Ye Kai team size is not large, but this small team in a short period of time has made a lot of results.
the most influential of these, counting their recent work on opium poppies, published in the journal Science.
the study lasted more than two years, and after completing the data collection, Ye Kai team members completed the difficult data analysis task efficiently in just eight months.
Says the secret to team quickness is to take advantage of cross-disciplines.
a careful analysis of the academic history of Ye Kai team members reveals that the team members have a rich academic background, covering a wide range of disciplines, including automation, computer science, biology, and more.
it is because team members use their years of knowledge and experience in their respective fields to ensure that every aspect of the research project is innovative and rigorous, in a very short period of time can be the best of the benefits of all parties.
at the same time, internationalization is another prominent feature of Ye Kai's Young Scientist synod.
in Ye Kai's view, a good team must have a broad vision and active international standards.
Guo Li is the first author of the article "The Genome of Opium Poppy and the Synthesis of Morphine Mutters."
joined Ye Kai's Young Scientist Studio at Xi'an Jiaotong University after completing his postdoctoral research in plant pathogens in the United States in 2016.
" and Professor Ye Kai get along, and I feel like a teacher and friend.
he has given us a relatively relaxed and free atmosphere of research, and I believe members can go further on this platform.
," Guo said.
" studio provides every young teacher with free space for development and personalized training programs.
"Ye Kai hopes to do his best to motivate team members and stimulate their research autonomy, " so that each member can grow into a unique talent."
Source: Science Daily.