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In recent years, the market size and growth rate of plant extracts have continued to expand. Data show that the global plant extract market is worth about $23.7 billion in 2019 and is expected to reach $59.4 billion by 2025, with a compound annual growth rate of 16.5% in 2019-2025.
that plants contain phenols, polysaccharides, saponins, alkaloids and other active ingredients, phenolic substances are one of its key components. Phenols are sensitive, susceptible to environmental factors, and have low solubility in water, and their biological utilization rate is always a difficult problem. How to improve the biological utilization rate of phenolic substances is an urgent problem in the industry.
phenol compounds are secondary metabolites synthesized from a combination of turbid acid, glyphosate and phenopropane, and are widely distributed in the plant community, and more than 8000 structures have been identified. The study points out that phenols have antioxidant activity, can remove free fundamentals, reduce lipid oxidation and DNA damage, is widely used in food, medicine, cosmetics and other fields. In addition, phenolic substances can also participate in the metabolic processes of cells, playing a special role in different metabolic pathways.
plants often store phenolic compounds in important locations as signals or plant defense mechanisms, so extraction is not easy. With the development of modern molecular extraction technology, the extraction efficiency of phenolic substances has been greatly improved, which can meet the development needs of industrialization.
encumeration technology is a processing technique often used in unstable ingredients, including phenols, which can not only prolong the storage period of active ingredients, improve stability, but also increase the likely contact between ingredients and the intestines, thus effectively increasing utilization rate. The key to the burying technology lies in the selection of the package material and the establishment of the package material system, which can be divided into emulsion, cyclodext and lipid body according to the simple to complicated process.
emulsion is the simplest burial system, is the oil-water two-phase mixture after adding emulsion homogeneity, whether it is water-wrapped emulsion or oil-wrapped water-based emulsion can provide a better "hiding" for phenolic substances, so that lipids are digested in the stomach to release active ingredients, improve utilization rate. However, because emulsions require emulsions and surfactants, their safety and health are slightly worse.
cyclycical dexterin is the general designation of a series of ring-shaped lysosaccharides produced by the cyclodextremic glucose-based transferase produced by Bacillus spores, and its molecules have a slightly conical three-dimensional ring structure of the hollow cylinder, thus allowing the active ingredient to enter its cavity. Depending on the structure and size of the cavity, it can be divided into alpha, beta and gamma configurations, of which beta and gamma types are the most commonly used types. The encumulation effect of cyclodext can first improve the stability of the ingredients, so as to protect them from light, heat and other factors, secondly, can increase the solubility of the active ingredients, its typical internal hydrophobic hydrophobic properties, not only can firmly lock the internal active ingredients, but also rely on external hydrophobic action can improve the solubility;the formation principle of
lipids is that lipid molecules are spontaneously and orderly arranged in water into a bimolele spory structure, while the water-soluble substance is encapsulated in the hydro-hydrokernel, while the fat-soluble substance is encapsulated in the hydrophosphate double molecular layer of hydrophosphate hydrophosphageal tail, thus showing the dual affinity of hydrophosphate, which can make the composition complex extract maximize the burying efficiency, its encapsulation efficiency of more than 92%. However, because the properties of lipids themselves are not stable enough, they are not mature enough in application.
present, in the active ingredients buried, the application of cyclodextyte mature, it has been used in food, medicine and other fields to mask the adverse odor of the active substance, increase solubility, stability and bio-use. From the development point of view, lipid body is the future direction of the development of encumeration technology, which not only has high burying efficiency, but also shows excellent targeting, which is very beneficial to the functional embodiment.
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