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Image source: Pixabay.
Source Cell Press Compilation.
Life experience tells us that the combination of work and rest is very important.
Proper relaxation can make people engage in study and work in a better state
.
A new study published recently also found that in a waking and resting state, brain activity can "play back" the sequence of actions just learned at 20 times the speed.
This process may be very important for memory consolidation
.
The research was published in Cell Reports on June 8
.
"Our research has demonstrated for the first time that humans will perform neural replay of the skills they have just learned when they are awake
.
This is also the first to prove that neural replay activity when awake can predict the rapid consolidation of memory, which is essential for early learning
.
"Senior research author Leonardo G.
Cohen said
.
Cohen works for the National Institute of Neurological Disorders and Stroke (NINDS), a subsidiary of the National Institutes of Health
.
What does the brain do during rest? When learning a new skill, if frequent breaks are inserted during the practice time, memory consolidation and performance will be improved
.
This phenomenon is called the spacing effect and has been proven in many tasks
.
The consolidation of memory during wakefulness occurs within a few seconds to a few minutes, and its consolidation amplitude is about 4 times that of the post-sleep memory consolidation that the classic research focuses on
.
But until now, the scientific community has not been clear how the brain combines discrete action representations into a unified, clear temporal sequence of actions in the resting state (that is, the waking state of relaxation)
.
One possible mechanism is neural replay, that is, during rest, the neural activity pattern representing the behavior sequence is reactivated and compressed in time, as if the neural activity has been added "fast forward"
.
The first author of the study, Ethan R.
Buch of NINDS, said: “Nerve replay in the resting state may replay previous exercises offline and promote the consolidation of skills in the awake state.
This problem has not been carried out in human or animal models before.
Research
.
"The truth about the combination of work and rest.
To verify this idea, the researchers used a brain imaging technology called magnetoencephalography (MEG)
.
Thirty subjects repeatedly typed "41324" on the keyboard as quickly and accurately as possible.
Each experiment lasted 10 seconds, repeated 36 times, and rested for 10 seconds between experiments
.
MEG data showed that their brains had a neural replay of the key sequence in the resting state
.
The neural replay only lasts 50 milliseconds, and the speed is 20 times faster than the actual action
.
Compared with the rest time before or after training, the frequency of neural replay is about three times higher in the rest time between two exercises
.
In addition, compared with the previous 11 experiments, during the rest time between the last 11 experiments, the frequency of neural replay was higher, and the subjects learned faster at this time
.
In addition, replaying events more frequently during breaks during practice is associated with greater skill consolidation
.
The brain network involved in neural replay includes the hippocampus, sensorimotor and entorhinal areas
.
"The deep involvement of the hippocampus and temporal lobes in procedural motor memory is surprising, because this type of memory activity is generally considered to not require the involvement of the hippocampus," Buch said.
"In general, our data shows that static Frequent and rapid neural replay will strengthen the association between the hippocampus and neocortex activated in previous exercises.
This process is related to improving subsequent performance and consolidating skills during wakefulness
.
"Looking forward, the researchers plan to use non-invasive Sexual brain stimulation, to test whether awake replay plays a causal role in early skill learning, and to determine whether rapid consolidation can also strengthen other types of memory
.
"Finally, understanding the characteristics of awake replay that are important for skill learning can help optimize treatment plans or determine better brain stimulation strategies, and improve the effects of rehabilitation after strokes and other brain injuries," Cohen said
.
Reference source: https://eurekalert.
org/pub_releases/2021-06/cp-hbr060321.
php Paper information [Title] Consolidation of human skill linked to waking hippocampo-neocortical replay [Author] Ethan R.
Buch, Leonardo Claudino, Romain Quentin, Marlene Bönstrup, Leonardo G.
Cohen [Journal] Cell Reports [Date] JUNE 08, 2021 [DOI] https://doi.
org/10.
1016/j.
celrep.
2021.
109193 [Link] https:// com/cell-reports/fulltext/S2211-1247(21)00539-8 【Abstract】The introduction of rest intervals interspersed with practice strengthens wakeful consolidation of skill.
The mechanisms by which the brain binds discrete action representations into consolidated, highly temporally resolved skill sequences during waking rest are not known.
To address this question, we recorded magnetoencephalography (MEG) during acquisition and rapid consolidation of a sequential motor skill.
We report the presence of prominent,fast waking neural replay during the same rest periods in which rapid consolidation occurs.
The observed replay is temporally compressed by approximately 20-fold relative to the acquired skill, is selective for the trained sequence, and predicts the magnitude of skill consolidation.
Replay representations extend beyond the hippocampus and entorhinal cortex to the contralateral sensorimotor cortex.
These results document the presence of robust hippocampo-neocortical replay supporting rapid wakeful consolidation of skill.
Replay representations extend beyond the hippocampus and entorhinal cortex to the contralateral sensorimotor cortex.
These results document the presence of robust hippocampo-neocortical replay supporting rapid wakeful consolidation of skill.
Replay representations extend beyond the hippocampus and entorhinal cortex to the contralateral sensorimotor cortex.
These results document the presence of robust hippocampo-neocortical replay supporting rapid wakeful consolidation of skill.
Source Cell Press Compilation.
Life experience tells us that the combination of work and rest is very important.
Proper relaxation can make people engage in study and work in a better state
.
A new study published recently also found that in a waking and resting state, brain activity can "play back" the sequence of actions just learned at 20 times the speed.
This process may be very important for memory consolidation
.
The research was published in Cell Reports on June 8
.
"Our research has demonstrated for the first time that humans will perform neural replay of the skills they have just learned when they are awake
.
This is also the first to prove that neural replay activity when awake can predict the rapid consolidation of memory, which is essential for early learning
.
"Senior research author Leonardo G.
Cohen said
.
Cohen works for the National Institute of Neurological Disorders and Stroke (NINDS), a subsidiary of the National Institutes of Health
.
What does the brain do during rest? When learning a new skill, if frequent breaks are inserted during the practice time, memory consolidation and performance will be improved
.
This phenomenon is called the spacing effect and has been proven in many tasks
.
The consolidation of memory during wakefulness occurs within a few seconds to a few minutes, and its consolidation amplitude is about 4 times that of the post-sleep memory consolidation that the classic research focuses on
.
But until now, the scientific community has not been clear how the brain combines discrete action representations into a unified, clear temporal sequence of actions in the resting state (that is, the waking state of relaxation)
.
One possible mechanism is neural replay, that is, during rest, the neural activity pattern representing the behavior sequence is reactivated and compressed in time, as if the neural activity has been added "fast forward"
.
The first author of the study, Ethan R.
Buch of NINDS, said: “Nerve replay in the resting state may replay previous exercises offline and promote the consolidation of skills in the awake state.
This problem has not been carried out in human or animal models before.
Research
.
"The truth about the combination of work and rest.
To verify this idea, the researchers used a brain imaging technology called magnetoencephalography (MEG)
.
Thirty subjects repeatedly typed "41324" on the keyboard as quickly and accurately as possible.
Each experiment lasted 10 seconds, repeated 36 times, and rested for 10 seconds between experiments
.
MEG data showed that their brains had a neural replay of the key sequence in the resting state
.
The neural replay only lasts 50 milliseconds, and the speed is 20 times faster than the actual action
.
Compared with the rest time before or after training, the frequency of neural replay is about three times higher in the rest time between two exercises
.
In addition, compared with the previous 11 experiments, during the rest time between the last 11 experiments, the frequency of neural replay was higher, and the subjects learned faster at this time
.
In addition, replaying events more frequently during breaks during practice is associated with greater skill consolidation
.
The brain network involved in neural replay includes the hippocampus, sensorimotor and entorhinal areas
.
"The deep involvement of the hippocampus and temporal lobes in procedural motor memory is surprising, because this type of memory activity is generally considered to not require the involvement of the hippocampus," Buch said.
"In general, our data shows that static Frequent and rapid neural replay will strengthen the association between the hippocampus and neocortex activated in previous exercises.
This process is related to improving subsequent performance and consolidating skills during wakefulness
.
"Looking forward, the researchers plan to use non-invasive Sexual brain stimulation, to test whether awake replay plays a causal role in early skill learning, and to determine whether rapid consolidation can also strengthen other types of memory
.
"Finally, understanding the characteristics of awake replay that are important for skill learning can help optimize treatment plans or determine better brain stimulation strategies, and improve the effects of rehabilitation after strokes and other brain injuries," Cohen said
.
Reference source: https://eurekalert.
org/pub_releases/2021-06/cp-hbr060321.
php Paper information [Title] Consolidation of human skill linked to waking hippocampo-neocortical replay [Author] Ethan R.
Buch, Leonardo Claudino, Romain Quentin, Marlene Bönstrup, Leonardo G.
Cohen [Journal] Cell Reports [Date] JUNE 08, 2021 [DOI] https://doi.
org/10.
1016/j.
celrep.
2021.
109193 [Link] https:// com/cell-reports/fulltext/S2211-1247(21)00539-8 【Abstract】The introduction of rest intervals interspersed with practice strengthens wakeful consolidation of skill.
The mechanisms by which the brain binds discrete action representations into consolidated, highly temporally resolved skill sequences during waking rest are not known.
To address this question, we recorded magnetoencephalography (MEG) during acquisition and rapid consolidation of a sequential motor skill.
We report the presence of prominent,fast waking neural replay during the same rest periods in which rapid consolidation occurs.
The observed replay is temporally compressed by approximately 20-fold relative to the acquired skill, is selective for the trained sequence, and predicts the magnitude of skill consolidation.
Replay representations extend beyond the hippocampus and entorhinal cortex to the contralateral sensorimotor cortex.
These results document the presence of robust hippocampo-neocortical replay supporting rapid wakeful consolidation of skill.
Replay representations extend beyond the hippocampus and entorhinal cortex to the contralateral sensorimotor cortex.
These results document the presence of robust hippocampo-neocortical replay supporting rapid wakeful consolidation of skill.
Replay representations extend beyond the hippocampus and entorhinal cortex to the contralateral sensorimotor cortex.
These results document the presence of robust hippocampo-neocortical replay supporting rapid wakeful consolidation of skill.
