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Young flora restores aging-related changes in mouse brains |
A new study claims that transplanting the intestinal flora of young mice to older mice can counteract specific changes in the brains of mice that are associated with aging
.
These findings suggest that such transplants may have therapeutic potential for aging-related cognitive decline
The microorganisms living in the body and on the surface of the human body have an impact on health and change with age
.
Those microorganisms that cause chronic inflammation, metabolic dysfunction and disease may gradually replace "friendly" microorganisms-those that have a beneficial effect on the metabolism and immune system
John Cryan, Marcus Boehme and colleagues of the University of Cork in Ireland transplanted fecal bacteria from young mice (3-4 months old) or old mice (19-20 months old) to old mice (19-20 months old)
.
The research team found that the immune system changes associated with aging in old mice were reversed after transplanting the flora of young mice
The authors concluded that these findings indicate that the intestinal flora may have the potential to be a therapeutic target in order to promote healthy aging
.
Further research is needed in the future to explore how specific bacteria or their metabolites work
Related paper information: https://doi.
https://doi.
org/ 10.
1038/s43587-021-00093-9 https://doi.
org/ 10.
1038/s43587-021-00093-9