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AbbVie IL-23 inhibitor approved in China for clinical treatment of Crohn's disease
Time of Update: 2021-02-10
It's worth noting that AbbVie recently announced that risankizumab has reached the primary endpoint of the induction phase in two Phase 3 clinical trials for adult patients with moderate to severe Crohn's disease.
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Chinese scientists have successfully developed a new coronary antibody cocktail therapy
Time of Update: 2021-02-10
Huang Zhong Research Group, Shanghai Pasteur Institute, Chinese Academy of Sciences, Molecular Cell Science Innovation Center, Xie Yuhua Group of Fudan University School of Medicine and Deng Qiang R
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Schizophrenia is associated with abnormal connections between the small brain and brain function
Time of Update: 2021-02-10
China Institute of Psychology Mental Health Key Laboratory Researcher Chen Chu overseas led a team of neuropsychology and applied cognitive neuroscience (NACN) in the early study found that schizophrenia patients and their unilever siblings in sensory integration processing there is a lack of activation of the brain, and the cer cerebral activation is significantly inheritable.
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The new achievements of China University of Science and Technology have opened up the bottleneck of blood shortage
Time of Update: 2021-02-10
The research team and team of Cheng Linyi, a professor at The University of Science and Technology of China, have recently made important progress in the direction of in-body production of red blood
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The application for the listing of the new crown vaccine for Coxing Zhongwei Bio-Crown was accepted by NMPA
Time of Update: 2021-02-10
recently, the industry came to the news that the new coronavirus inactivated vaccine (Kelleford) developed by Coxing Zhongwei Bio has been accepted by China's State Drug Administration (NMPA).
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NMN: Star API on the road to "Seal god"
Time of Update: 2021-02-02
NMN as a new star raw material, its full name niacinamide mononucleotide, is the reaction product of niacinamide phosphate RNA transferase, mainly as a key prelub of NAD plus in the body, through transformation to play physiological functions, such as activation of NAD-substrate dependent enzyme Sirt1 (histone deacetylase), regulation of cell survival, death and maintenance of oxidation reduction state.
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High-volume ITS sequencing into a diagnostic supplement for fungal corneitis
Time of Update: 2021-01-29
ITS high-flux sequencing of conjunctival swabs and corneal scraper tissue in these patients assumed that the relatively highest level of fungi in sequencing results was pathogenic, and the positive and consistent rates of culture and sequencing for diagnosis of pathogenic bacteria were evaluated.
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Solve the 100-year-old problem of cancer cell "energy plants"
Time of Update: 2021-01-29
"PI3 kinase is a key signaling molecule that functions almost like the commander-in-chief of cell metabolism.
Like immune cells, cancer cells may use Watts metabolism to maintain the activity of this signaling path, ensuring its continued growth and division.
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The mechanism of intestinal damage caused by heat-resistant enterotoxin in pigs has been revealed
Time of Update: 2021-01-29
The study for the first time analyzed STp through the targeting of Wnt/β-catenin signaling pathway, thereby changing the fate of intestinal stem cells, causing the mechanism of entero mucosal lesions, for the production of prevention and control of pig diarrhea provides a new way; (Source: China Science Journal Zhu Hanbin Chen Weichen) relevant paper information:
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The brain's "garbage dump" hides Parkinson's clues
Time of Update: 2021-01-29
study by Mr. Teng and others found that meninges lymphatic tube draination in patients with primary Parkinson's disease was impaired, and for the first time suggested a noninvasive method for assessing the relevant draination function as a sensitive indicator for early diagnosis of Parkinson's disease.
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Metal nanoenzymes have made important progress in the treatment of Parkinson's disease
Time of Update: 2021-01-22
In-body cell experiments have shown that PtCu nanoenzyme can significantly reduce the level of reactive oxygen (ROS) induced by PFF, α-synaptic nucleoprotein pathology and neurotoxicity, and, importantly, the nanoenzyme can also block the spread of pathological α-synaptic nuclear protein cells.
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Immunity may last up to 6 months after infection with the new crown
Time of Update: 2021-01-22
The authors conclude that the continued presence and evolution of memory B cells suggest that in the event of a new coronavirus re-infection, the human body may be able to quickly produce powerful virus-mediated antibodies.
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Wang and others have collaborated to develop mathematical models that can predict the effectiveness of immunotherapy
Time of Update: 2021-01-22
The team, led by Dr. Wang and Dr. Vittorio Cristini of the Methodist Institute in Houston, worked with researchers at the University of Texas MD Anderson Cancer Center to develop a machine-based mathematical model of checkpoint inhibitor immunotherapy that can be used to predict and quantify the response of specific cancers to specific immunotherapy therapies, thereby quantifying the success rate of treatment after using a specific combination of cancer-immunotherapy drugs for individual patients.
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Scientists have found new targets for treating lung metastasis in breast cancer
Time of Update: 2021-01-22
The research team of Hu Guohong of the Shanghai Institute of Nutrition and Health of the Chinese Academy of Sciences found that tissue protease C (CTSC) could be used as a therapeutic target for pulmonary metastatic breast cancer, and that AZD7986, a clinical stage II small molecule compound specifically inhibiting CTSC, could significantly inhibit breast cancer cell lung metastasis.
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Chinese scholars reveal the regulatory network and markers of the heartbeat "center"
Time of Update: 2021-01-22
What is the core gene regulation network that controls the function of sinus cells?
The researchers identified a core gene regulatory network that controls heart beats, where individual molecules have been shown to significantly regulate the frequency of heartbeats.
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The biological function of lupus genetic dark matter has been revealed
Time of Update: 2021-01-13
Based on these findings, the researchers speculate that disease susceptibility points located in enhanced subregions may act as a label for which disease susceptibility points in the genome are functional and which regulatory regions can participate in the development of SLE incidence.
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This toxin is more annoying than diarrhea
Time of Update: 2021-01-13
coli bacteria to invade the immune system, the key of which is the Zhiga toxin, the study was published in Science-Immunology.
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Chinese scholars find "gene therapy" to delay aging
Time of Update: 2021-01-13
Liu Guanghui, a researcher at the Institute of Zoology of the Chinese Academy of Sciences, and others have identified new aging regulatory genes in human-filled stem cells using the whole genome CRISPR/Cas9 screening system for the first time, and on this basis have developed a new "gene therapy" that can delay the aging of the body.
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Expect pulmonary hypertension patients to "take fewer detours"
Time of Update: 2021-01-12
Since the 1970s, experts and scholars represented by Cheng Hsiensheng, founder of the field of pulmonary hypertension in China and professor of pulmonary vascular disease diagnosis and treatment center of the Chinese Academy of Medical Sciences, have carried out hypoxic PH and other pulmonary vascular disease-related studies with pulmonary heart disease as the core, and have made a series of progress.
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It is revealed that the DNA of hepatitis B virus and human genome are landscaped
Time of Update: 2021-01-12
The study describes the characteristics of the interaction between HBV DNA and the host genome in the form of HBV DNA and integrated forms, providing new potential targets for the treatment of HBV infection and related diseases.
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