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Scientists in Nature sub-publish found that super nanoparticles other than exosomes are rich in disease biomarkers and therapeutic targets.
Time of Update: 2022-01-09
Professor Robert Coffey of Vanderbilt University Medical Center is a well-known intestinal tumor expert and is actively exploring whether the detection of Supermeres in the blood can achieve earlier diagnosis and treatment of diseases .
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Nature Sub-Journal: Not only exosomes, cells also contain super particles
Time of Update: 2021-12-28
Corresponding author, Professor Robert Coffey of Vanderbilt University Medical Center said: "We have identified multiple biomarkers and therapeutic targets for cancer and other disease states.
Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets.
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Nature sub-publishes the latest research progress of exosome delivery system, mediating anti-HIV effects attracting attention. Medical Maihei Technology
Time of Update: 2021-10-22
Recommended reading: Using exosome technology to deliver mRNA therapeutics in the bodyYimai Meng broke the news.
Evox Therapeutics is an exosome technology developer and DeliverEX platform is the company's proprietary exosome delivery platform .
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Chinese scholar Nature published an article: Regulatory T cell exosomes intelligently deliver VEGF antibodies
Time of Update: 2021-07-30
To this end, the State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, based on exosomes derived from Treg in vivo (rEXS) and clinically available VEGF antibody drugs, proposed "temporal and spatial coupling" delivery and "anti-VEGF-anti-inflammatory" synergistic therapy In conjunction with the new strategy of Beijing Chaoyang Hospital and the University of Queensland, the research and development of new drugs for the treatment of fundus neovascular diseases has been carried out .
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Nature Nanotechnology: Relaxin relieves liver fibrosis through liver macrophage exosomes
Time of Update: 2021-04-17
Using nanoparticle-mediated delivery, Professor Huang Lifu’s team found that although enhancing the expression of relaxin in fibrotic liver in vivo has a strong anti-fibrotic effect, in vitro treatment cannot reverse the static phenotype of activated hepatic stellate cells , Indicating that the microenvironment surrounding aHSCs promotes relaxin-mediated anti-fibrosis.
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Nature's latest report says exosomes will soon be used clinically
Time of Update: 2020-12-31
's other important candidate, exoIL-12, is an engineered exosome that has been engineered to express inflammable IL-12 on its surface, and is currently undergoing Phase I clinical trials in patients with early-stage skin T-cell lymphoma.
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Nature: Super-magical new immune mechanism! Scientists have discovered for the first time
Time of Update: 2020-07-21
(source: med.nyu.edu )Based on previous studies, Cadwell and Torres have known that the pore forming toxin secreted by bacteria will bind with ADAM10 on the cell surface, resulting in cell membrane perforation [5].