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A novel adamantane-type PPAP pain relief molecule with significant Cav3.2 T-type calcium channel inhibition
Time of Update: 2023-01-06
8;font-family:;font-size:12pt;}Polycyclic polyprenylated acylphloroglucinol (PPAP) is a class of natural products with heterozygotic pathways, mainly including bridge ring type, adamantane type and further cracking ring due to the above two architecture types, Rearrangement and sidechain looping of its precursors results in a variety of structurally diverse derivative structure types.
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A novel adamantane-type PPAP pain relief molecule with significant Cav3.2 T-type calcium channel inhibition
Time of Update: 2023-01-06
8;font-family:;font-size:12pt;}Polycyclic polyprenylated acylphloroglucinol (PPAP) is a class of natural products with heterozygotic pathways, mainly including bridge ring type, adamantane type and further cracking ring due to the above two architecture types, Rearrangement and sidechain looping of its precursors results in a variety of structurally diverse derivative structure types.
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Tianchen develops a new type of calcium carbide furnace heat exchange system
Time of Update: 2022-04-25
Previously, Tianchen Calcium Carbide Plant's calcium carbide furnace heat exchange system adopted softened water process, which resulted in large water consumption and unqualified water quality, which affected the normal operation of calcium carbide furnace equipment .
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From hard to soft: the preparation and application of a new type of calcium carbonate
Time of Update: 2022-03-23
In addition, the researchers expect that because of the biocompatibility of calcite, SC will have value in biomedical applications and the preparation of new composite materials .
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CSPC submits 4 types of generic marketing applications for rosuvastatin calcium tablets
Time of Update: 2022-03-03
When the rosuvastatin reported for production this time is successfully approved, it will soon become the company's fourth It is a lipid-lowering drug, and at the same time, it has increased the product line of CSPC in the field of blood lipid regulators .
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The closed-state inactivation of human N-type voltage-gated calcium channel CaV2.2 and its drug regulation mechanism
Time of Update: 2021-11-14
Voltage-gated calcium channels (Ca V ) are widely present in the human body and are closely related to a series of important physiological processes such as muscle contraction, neurotransmitter release, and pain perception .
This study reveals for the first time the structural basis of closed-state inactivation of voltage-gated calcium channels .
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New drugs for extra-use of plaque-type psoriasis! FDA approves Wynzora (calcium poisol/ dipropyl acid fentamisopine) cream!
Time of Update: 2020-07-31
, the company announced that the U.S. Food and Drug Administration (FDA) has approved The Wynzora cream (calcium pobutan and glycemic acid fentamitol, w/w, 0.005%/0.064 percent) as a daily external therapy for the treatment of plaque-type psoriasis in adults up to 18 years of age.
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Discovery of a novel rosin type T-type calcium channel agonist in Salvia in Kangding
Time of Update: 2019-08-03
It is an important source of innovative drug research and development to explore novel and active compounds from characteristic medicinal plant groups Salvia is one of the most widely used medicinal p
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A novel rosin type T-type calcium channel agonist has been found
Time of Update: 2019-07-12
It is an important source of innovative drug research and development to explore new compounds with novel structure and significant activity from characteristic medicinal plant groups Salvia is one of