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[Nature Sub-Journal] The 3D pancreatic cancer tumor model cultivated by an international team
Time of Update: 2021-09-30
In a new study published in "Nature Communications" on September 24, researchers from the University of Nottingham, Queen Mary University of London, Monash University and Shanghai Jiaotong University created a multicellular three-dimensional microenvironment that uses patient sources The cells reproduce the growth pattern of tumor cells in pancreatic cancer and respond to chemotherapy drugs .
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3D tumor model is expected to achieve precise treatment of pancreatic cancer
Time of Update: 2021-09-28
David Osuna de la Peña, the first author of this article, said: "There are two main obstacles to the treatment of pancreatic cancer-the presence of high density of stromal cells and extracellular matrix and highly drug-resistant cancer stem cells (CSC) .
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3D bioprinting models transform cancer drug development and tumor therapy
Time of Update: 2021-02-09
In the study, recently published in Advanced Materials, Dr. Angela Panoskaltsis-Mortari, associate director of research at the University of Minnesota School of Medicine, professor of pediatrics, director of the 3D Bioprinting Equipment Department and a member of the Masonic Cancer Center, and her assistant researchers found that cells behave differently in these 3D flexible tissue environments than on 2D plastic or glass surfaces.
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Sci Adv: A new 3D tumor model developed in the lab may help improve treatment for ovarian cancer.
Time of Update: 2020-10-23
Photo Source: Alvaro Mata Researchers now need an improved version of the 3D cancer model to study tumor growth, progression, and response to new therapies in ovarian cancer patients, with 90 percent of successful cancer treatments tested in preclinical trials failing in early clinical trials and less than 5 percent of cancer drugs successfully used in clinical trials, and preclinical trials relying on 2D lab-grown cell cultures and animal models to predict patient responses to treatments.
