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 Home > Popular Keywords > Keyword List C > comet dna

comet dna

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Oxidation of Cellular DNA Measured with the Comet Assay

 Time of Update: 2020-12-29

The comet assay, or alkaline single-cell gel electrophoresis, originated as a simple and sensitive method for detectingDNA strand breaks in cells such as peripheral blood lymphocytes, cultured cells, and disaggregated tissue, e.g., liver ( 1 , 2 ). DNA is drawn out of the nucleoid to form a “comet tail” ( see Note 1 ).
Measurement of DNA Damage Using the Comet Assay

 Time of Update: 2020-12-28

Nitric oxide (NO) has the potential to damageDNA directly, and also to react with O 2 to form the nitrosating species N 2 O 3 or to react with O 2 − to form the powerful oxidizing agent peroxyni
Biomarkers of Oxidative Stress: Methods and Measures of Oxidative DNA Damage (COMET Assay) and Telomere Shortening

 Time of Update: 2020-12-09

Telomere length measured by Southern blotting technique allows one to estimate the chronic burden of oxidative stress at the molecular level and is now considered as biomarker of biological aging.

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