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Use one type of immune cell to target another
Time of Update: 2022-10-31
Researchers at the Icahn School of Medicine at Mount Sinai in New York say a new cancer immunotherapy that uses one immune cell to kill another cell, rather than directly attacking cancer, will stimulate a powerful anti-tumor immune response to shrink ovarian, lung and pancreatic tumors in preclinical disease models.
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Professor Beicontinental Jian's Review: Excessive negative regulation of type I interferon
Time of Update: 2022-10-26
▲ Click the blue word above to follow CellPress cell science ▲ Life SciencesLife scienceAs the world's leading academic publisher in the field of all-science, Cell Press has cooperated with the "Youth
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It's not just neurons that cause pain, there are another type of cell!
Time of Update: 2022-10-25
In a study published Oct. 7 in Science Advances, the team dubbed the phenomenon a "macrophage-to-neuron-like transition," or MNT, which may explain why some cancer patients are unable to relieve pain by using traditional painkillers, said co-author Patrick Tang, a biochemist at Chinese University in Hong Kong.
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No longer a "sweet burden", novel T-cell therapies promise to treat/prevent type 1 diabetes
Time of Update: 2022-10-20
▎WuXi AppTec Content Team Editor Type 1 diabetes mellitus (T1D) is an organ-specific autoimmune disease that results from autoreactive T cells targeting β cells used to produce insulin in pancreatic i
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Diabetologia: Detection of enterovirus RNA in peripheral blood mononuclear cells is associated
Time of Update: 2022-10-19
Detection of enterovirus RNA in peripheral blood mononuclear cells correlates with the presence of the predisposing allele of the type 1 diabetes risk gene IFIH1 and with disease stage.
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Diabetologia: Detection of enterovirus RNA in peripheral blood mononuclear cells is associated
Time of Update: 2022-10-19
Detection of enterovirus RNA in peripheral blood mononuclear cells correlates with the presence of the predisposing allele of the type 1 diabetes risk gene IFIH1 and with disease stage.
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New research in Cell details the microbial origins of type 1 diabetes
Time of Update: 2022-10-19
About a decade ago, UO graduate student Jennifer Hampton Hill made a serendipitous discovery: a protein produced by gut bacteria that triggers insulin-producing cells to replicate.
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A special type of droplet related to stem cell differentiation could provide a target for new cancer therapies
Time of Update: 2022-10-13
In studying the stem cell differentiation pathway, researchers at the University of California, Santa Barbara, found that all the proteins involved did not form assembly lines or rigid structures, but combined into a single droplet.
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Cell Rep: Metabolic disorders are common in different organs in patients with type 2 diabetes
Time of Update: 2022-10-13
In fully developed type 2 diabetes, there are broader abnormalities, such as lipid and glucose metabolism, as well as energy production of liver, muscle and fat," said Professor Claes Wadelius, who coordinated the study.
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Over the past 30 years, allogeneic hematopoietic stem cell transplantation outcomes in patients
Time of Update: 2022-10-13
Figure 2 RR and NRM in patients undergoing allo-HSCT in different disease states and at different timesIn addition, in patients transplanted during CR1, the improvement in RR in Ph+ patients over time was more pronounced than in non-Ph patients, with a 5-year corrected RR of 39.
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"Cell": Scientists reveal immune profiles of different tumor types
Time of Update: 2022-10-12
In a study titled "Discovering dominant tumor immune archetypes in a pan-cancer census" published in Cell, UCSF and multiple research teams identified and classified immune archetypes in 12 different tumor types.
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"Cell": Scientists reveal immune profiles of different tumor types
Time of Update: 2022-10-12
In a study titled "Discovering dominant tumor immune archetypes in a pan-cancer census" published in Cell, UCSF and multiple research teams identified and classified immune archetypes in 12 different tumor types.
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Cell: Based on 35 cancer types, the mechanism of cancer-microbial interaction has been discovered
Time of Update: 2022-10-12
On September 29, a study conducted by foreign scientists comparing fungal communities within tumors with matched bacterial and immune groups revealed a co-occurring dual-domain ecology, often with a loose rather than competitive microenvironment and different immune responses.
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ARD: The Huayinghui team revealed that type II collagen promotes gouty arthritis by regulating sodium urate crystals and inflammatory cell recruitment
Time of Update: 2022-10-12
On September 15th, the Hua Yinghui team of the Department of Sports Medicine of Huashan Hospital affiliated to Fudan University carried out research based on clinical surgical experience, combined wi
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Nature "pushes" neurodegeneration from the immune state: clonally amplified CD8 T cells can serve
Time of Update: 2022-10-01
Written by | QiAmyotrophic lateral sclerosis (ALS, also known as frostbite) is a heterogeneous neurodegenerative disease that affects motor neurons and voluntary muscle control. Disease-causing mutati