2021 ACR: The relationship between intra-articular mineralization on CT of the knee joint and the risk of cartilage loss: a multicenter osteoarthritis study

Background / Objective : Intra-articular (IA) mineralization caused by crystal deposition may lead to osteoarthritis ( OA )
through inflammation, release of pro-catabolism factors, or changes in the biomechanical properties of cartilage .

Previous studies on whether chondrocalcinosis (from IA mineralization) are related to the progress of OA structure are contradictory, and further research is limited by the low sensitivity of X- ray visualization of IA mineralization

BACKGROUNDBackground / / Objective Objective : crystal deposition due intraarticular (IA) mineralization by inflammation may promote or alter the release of decomposition biomechanical properties of cartilage metabolism factors lead to osteoarthritis ( OA ) is generated

MethodMethod : This is a longitudinal prospective cohort, multicenter from osteoarthritis (MOST) older studies conducted knee CT and the MRI

ResultsResults : The study included 1673 participants (mean age 60.

ConclusionConclusion : cartilage within the joint mineralization, rather than the meniscus mineralization, associated with a higher risk two years in the same compartment cartilage loss

 

Source:

Source:

Liew J, Lynch J, Guermazi A, Jarraya M, Felson D, Wang N, Lewis C, Torner J, Nevitt M, Neogi T.

Intra-Articular Mineralization on Knee CT and Risk of Cartilage Loss: The Multicenter Osteoarthritis Study [abstract] .

Liew J, Lynch J, Guermazi A, Jarraya M, Felson D, Wang N, Lewis C, Torner J, Nevitt M, Neogi T.
Intra-Articular Mineralization on Knee CT and Risk of Cartilage Loss: The Multicenter Osteoarthritis Study [abstract] .
Arthritis Rheumatol.
Arthritis Rheumatol.
 2021; 73 (suppl 10).
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