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    Home > Active Ingredient News > Immunology News > 6 kinds of Chinese patent medicines commonly used in rheumatoid, you must know!

    6 kinds of Chinese patent medicines commonly used in rheumatoid, you must know!

    • Last Update: 2022-08-16
    • Source: Internet
    • Author: User
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    The theory of traditional Chinese medicine believes that rheumatism is caused by wind, cold, dampness, heat and other external pathogens invading the human body, blocking the meridians, and causing the poor circulation of qi and blo.


    The theory of traditional Chinese medicine believes that rheumatism is caused by wind, cold, dampness, heat and other external pathogens invading the human body, blocking the meridians, and causing the poor circulation of qi and blo.


    Because of its association with autoimmunity , most patients require lifelong medicati.


    Tripterygium series

    Composition: It contains alkaloids such as triptolide, triptolide, triptolide , triptolide, and other ingredients such as scutellol, eudol, triptolide, glucose, and tann.


    Composition:Composition: Contains triptolide, triptolide, triptolide, triptolide and other alkaloids, as well as anthophylol , eudol, triptolide, glucose, tannin and other ingredien.


    Indications: expel wind and detoxify, dehumidify and reduce swelling, relax tendons and dredging collatera.


    Indications:Indications: expelling wind and detoxifying, dehumidifying and swelling, relaxing tendons and dredging collatera.


    Indicating syndrome types:Indicating syndrome types: Tripterygium wilfordii is mainly used to treat rheumatism-heat arthralgia syndro.


    Modern pharmacological research:Modern pharmacological research:

    (1) Immunomodulatory effect: Tripterygium wilfordii can correct the disorder of T cell subsets, inhibit B cell proliferation, regulate the level of immune molecules in both directions, and reduce peripheral blood IgG and I.


    (1) Immunomodulatory effect: Tripterygium wilfordii can correct the disorder of T cell subsets, inhibit B cell proliferation, regulate the level of immune molecules in both directions, and reduce peripheral blood IgG and I.


    (2) Anti-inflammatory effect: Tripterygium wilfordii can inhibit the increase of vascular permeability and the chemotaxis of inflammatory cells, thereby playing an anti-inflammatory effect on joint inflammati.


    Paeony Glycosides Capsules

    Composition: The main components are hydroxypaeoniflorin, paeoniflorin, paeoniflorin, paeoniflorin, e.


    Composition:Composition: The main components are hydroxypaeoniflorin, paeoniflorin, paeoniflorin, paeoniflorin, e.


    Indications:Indications: rheumatoid arthrit.


    Indication syndrome type:Indication syndrome type: main evil qi abdominal pain, eliminate blood paralysis, break hard accumulation, treat cold and heat hernia, relieve pain, facilitate urination, and invigorate .


    Modern pharmacological research:Modern pharmacological research: As an immunomodulatory drug, total glucosides of paeony have a two-way regulatory effe.


    Zhengqing Fengtongning Tablets

    Composition: The main components are sinomenine and bi-sinomeni.

    Composition:Composition: The main components are sinomenine and bi-sinomeni.

    Indications: expelling wind and dampness, promoting blood circulation and dredging collaterals, reducing swelling and relieving pa.

    For rheumatoid arthritis, rheumatoid arthritis and other patien.

    Indications:Indications: expelling wind and dampness, promoting blood circulation and dredging collaterals, reducing swelling and relieving pa.

    For rheumatoid arthritis, rheumatoid arthritis and other patien.

    Indications: Zhengqing Fengtongning Tablet mainly treats wind-cold-damp-arthritis syndro.

    Wind-cold-damp-arthralgia is mainly characterized by pain and swelling of muscles, bones and joints, numbness of limbs, unfavorable stretching, aversion to wind and chills, decreased pain in case of heat, increased pain in case of cold, thin white or greasy tongue coating, and tight or stringy or slippery pul.

    clinical featur.

    Wind-cold-dampness arthralgia can be divided into action arthralgia, pain arthralgia, and impingement arthralg.

    Those with arthralgia can wander unsteadily and aversion to wind-cold; arthralgia patients have severe pain, severe in case of cold, and slowed down when heated; those with arthralgia are seve.

    Pain due to contact, heavy hands and feet, immobility, and numbness of the skin; its treatment is mainly to expel wind and dampness, warm the meridians and dispel cold, and relieve pain by dredging collatera.

    Indication syndrome:Indication syndrome: Zhengqing Fengtongning Tablet mainly treats wind-cold-damp-arthritis syndro.

    Wind-cold-damp-arthralgia is mainly characterized by pain and swelling of muscles, bones and joints, numbness of limbs, unfavorable stretching, aversion to wind and chills, decreased pain in case of heat, increased pain in case of cold, thin white or greasy tongue coating, and tight or stringy or slippery pul.

    clinical featur.

    Wind-cold-dampness arthralgia can be divided into action arthralgia, pain arthralgia, and impingement arthralg.

    Those with arthralgia can wander unsteadily and aversion to wind-cold; arthralgia patients have severe pain, severe in case of cold, and slowed down when heated; those with arthralgia are seve.

    Pain due to contact, heavy hands and feet, immobility, and numbness of the skin; its treatment is mainly to expel wind and dampness, warm the meridians and dispel cold, and relieve pain by dredging collatera.

    Modern pharmacological research: The active ingredients Sinomenine and Bisinomenine in Zhengqing Fengtongning Tablets have good anti-rheumatic and anti-inflammatory effects, and can selectively inhibit the activity of cyclooxygenase-2 and reduce the Synthesis of E2 in the prostate, and the drug has low gastrointestinal reactions after sustained relea.

    In the study of Liao Yong et .

    , it was found that the drug can improve the inflammatory response of patients well, and has a good inhibitory effect on inflammation, especially in anti-rheumati.

    The reason may be that Heptospora sinensis can regulate the production of cytokines by human lymphocytes, inhibit the expression of inflammatory factors such as IL-1, and can play a role in rheumatoid arthritis by down-regulating the expression of IL-8 in peripheral mononuclear cel.

    Modern pharmacological research:Modern pharmacological research: The active ingredients sinomenine and bi-sinomenine in Zhengqing Fengtongning Tablets have good anti-rheumatic and anti-inflammatory effects, and can selectively inhibit epoxidation Enzyme-2 activity, reducing the synthesis of E2 in the prostate, and the drug has low gastrointestinal reactions after sustained relea.

    In the study of Liao Yong et .

    , it was found that the drug can improve the inflammatory response of patients well, and has a good inhibitory effect on inflammation, especially in anti-rheumati.

    The reason may be that Heptospora sinensis can regulate the production of cytokines by human lymphocytes, inhibit the expression of inflammatory factors such as IL-1, and can play a role in rheumatoid arthritis by down-regulating the expression of IL-8 in peripheral mononuclear cel.

    Tongbiling Tablets

    Tongbiling Tablets

    Composition: The main ingredients are: cassia twig, centipede, buffalo horn, strychnine powder, windproof, atractylodes,e.

    Composition:Composition: The main ingredients are: cassia twig, centipede, buffalo horn, strychnine powder, windproof, atractylodes,e.

    Indications: expelling wind and dampness, promoting blood circulation and removing blood stasis, dredging collaterals and relieving pa.

    For rheumatoid arthritis, ankylosing spondylitis, cervical spondylosis,e.

    Indications:Indications: expelling wind and dampness, promoting blood circulation and removing blood stasis, dredging collaterals and relieving pa.

    For rheumatoid arthritis, ankylosing spondylitis, cervical spondylosis,e.

    Indication syndromes: Tongbiling tablets are mainly used to treat rheumatism invasion syndro.

    The rheumatism invasion type is mostly characterized by swelling and pain of muscles, bones and joints, but there is no local heat and cold, abnormal skin color, no preference for warmth or fear of cold, and pale tong.

    The main clinical features are red, greasy fur, and a floating and tight pul.

    The main treatment is to disperse wind and dehumidi.

    Indication syndrome:Indication syndrome: Tongbiling tablet mainly treats rheumatism invasion syndrome, rheumatism invasion type is mostly swelling and pain of muscles, bones and joints, but there is no local cold and heat, abnormal skin color, and no preference for warmth Or intolerance to cold, pale red tongue, greasy coating, and tight pulse are the main clinical featur.

    The main treatment is to disperse wind and dehumidi.

    Modern pharmacological research: Animal experiments show that Tongbiling tablets can significantly inhibit the proliferation of synovial fibroblas.

    At the same time, clinical observation shows that Tongbiling Tablet has various pharmacological effects such as anti-inflammatory, anti-rheumatic, immune regulation and physical improveme.

    The randomized controlled single-blind and double-dummy method was used to observe the clinical efficacy of Tongbiling tablets in the treatment of active ankylosing spondylit.

    similar , and there were no toxic side effec.

    It is more effective than indomethacin in eliminating swelling, shortening morning stiffness time, improving lumbar spine mobility, reducing finger-to-ground distance and overall joint functio.

    It has a significant improvement effect; it has a stable and improved effect on the bone destruction of ankylosing spondylit.

    Similarly, there is a study of 32 cases of ankylosing spondylitis treated with Tongbiling tablets: 7 cases were significantly improved, 23 cases were improved, and 2 cases were ineffecti.

    And no obvious toxic and side effects were observed in clinical observati.

    Modern pharmacological research:Modern pharmacological research: Animal experiments show that Tongbiling tablets can significantly inhibit the proliferation of synovial fibroblas.

    At the same time, clinical observation shows that Tongbiling Tablet has various pharmacological effects such as anti-inflammatory, anti-rheumatic, immune regulation and physical improveme.

    The randomized controlled single-blind and double-dummy method was used to observe the clinical efficacy of Tongbiling tablets in the treatment of active ankylosing spondylit.

    similar , and there were no toxic side effec.

    It is more effective than indomethacin in eliminating swelling, shortening morning stiffness time, improving lumbar spine mobility, reducing finger-to-ground distance and overall joint functio.

    It has a significant improvement effect; it has a stable and improved effect on the bone destruction of ankylosing spondylit.

    Similarly, there is a study of 32 cases of ankylosing spondylitis treated with Tongbiling tablets: 7 cases were significantly improved, 23 cases were improved, and 2 cases were ineffecti.

    And no obvious toxic and side effects were observed in clinical observati.

    Tongluo Kaibi Tablets

    Tongluo Kaibi Tablets

    Composition: Strychnine powder, safflower, Achyranthes, Angelica, Nepeta, Papaya, Fangfeng, Quan scorpi.

    Composition: Composition: strychnine powder, safflower, Achyranthes chinensis, angelica, nepeta, papaya, parsnip, and whole scorpi.

    Indications: It is suitable for mixed cold and heat, blood stasis and collaterals, rheumatoid arthritis, joint pain and swelli.

    Indications: Indications: suitable for mixed cold and heat, blood stasis blocking collaterals, rheumatoid arthritis, joint pain and swelli.

    Indication syndrome type: Tongluo Kaibi Tablet is mainly used to treat the syndrome of mixed cold and heat, blood stasis blocking collatera.

    Warm and cool, dark red tongue or petechiae, thin white fur, thin and astringent puls.

    The main treatment is to dispel cold and clear heat , and to clear the meridian.

    Indicating syndromes: Indicating syndromes: Tongluo Kaibi Tablet is mainly used to treat the syndrome of mixed cold and heat, blood stasis blocking the collaterals , and the cold and heat are mix.

    Fear of heat, partial liking of warm and cool joints, dark red tongue or tongue with petechiae and ecchymosis, thin white fur, thin and astringent puls.

    The main treatment is to dispel cold and clear heat , and to clear the meridian.

    Modern pharmacological research: strychnine is a monarch drug, the main components are strychnine and strychnine, strychnine has obvious analgesic effect, the results of modern pharmacological research show that strychnine and its nitrogen Oxygen compounds have significant analgesic, anti-inflammatory and anti- thrombotic effects, so strychnine is mainly used to open the meridians, penetrate the joints, and treat rheumati.

    Zhou Xiaoli et .

    compared the efficacy of Tongluo Kaibi Tablets combined with Leflunomide Tablets (n=36) and Leflunomide Tablets alone (n=36) in the treatment of .

    The results showed that the erythrocyte sedimentation rate of patients in the combined Chinese and Western medicine group (ESR), rheumatoid factor (RF), C-reactive protein (CRP) and immunoglobulin G (IgG) levels, clinical symptoms (time of morning stiffness, number of tender and swollen joints), visual analog scale for pain The improvement of DAS28 score was significantly better than that of leflunomide alone group, and the incidence of adverse reactions in the two groups was simil.

    Modern pharmacological research: Modern pharmacological research: strychnine is the king drug, the main components are strychnine and strychni.

    Strychnine and its nitrogen oxide compounds have significant analgesic, anti-inflammatory and antithrombotic effects, so strychnine is mainly used to open the meridians, penetrate the joints, and treat rheumati.

    Zhou Xiaoli et .

    compared the efficacy of Tongluo Kaibi Tablets combined with Leflunomide Tablets (n=36) and Leflunomide Tablets alone (n=36) in the treatment of .

    The results showed that the erythrocyte sedimentation rate of patients in the combined Chinese and Western medicine group (ESR), rheumatoid factor (RF), C-reactive protein (CRP) and immunoglobulin G (IgG) levels, clinical symptoms (time of morning stiffness, number of tender and swollen joints), visual analog scale for pain The improvement of DAS28 score was significantly better than that of leflunomide alone group, and the incidence of adverse reactions in the two groups was simil.

    thrombus

    Dahuoluodan

    Dahuoluodan

    Composition: Consists of Qi Snake (made with wine), Caowu (baked), Leopard Bone, Artificial Bezoar, Wushao Snake, Gastrodia elata, Cooked Rhubarb, Artificial Musk, Dried Blood, Rehmannia glutinosa, Tian Nanxing, Buffalo Horn Concentrated Powder, e.

    50 flavor compositi.

    Composition: Composition: composed of Qi Snake (made with wine), Caowu (burned), Leopard Bone, Artificial Bezoar, Wushao Snake, Gastrodia elata, cooked rhubarb, artificial musk, dried blood, Rehmannia glutinosa, Tiannanxing, buffalo horn Concentrated powder and other 50 flavo.

    Indications: expel wind, relax tendons, activate collaterals, and dehumidi.

    It is used for limb pain, numbness of hands and feet, muscle spasm, stroke paralysis, slanted mouth and eyes, hemiplegia, and slurred speech caused by wind-cold-dampness arthralg.

    Indications: Indications: expelling wind, relaxing tendons, activating collaterals, dehumidifyi.

    It is used for limb pain, numbness of hands and feet, muscle spasm, stroke paralysis, slanted mouth and eyes, hemiplegia, and slurred speech caused by wind-cold-dampness arthralg.

    Indicating syndromes: Dahuoluodan is mainly used to treat the syndrome of deficiency of qi and blo.

    The deficiency of qi and blood is mostly characterized by swelling and pain of muscles, bones and joints or less swelling and pain, pale complexion, fatigue, shortness of breath, spontaneous sweating, palpitations, and lack of fo.

    Loose stools, pale red tongue and lack of lubrication, yellow or thin white coating, and slow pul.

    Governance is mainly based on nourishing qi and nourishing blood, soothing meridians and activating collatera.

    Indicating syndrome types: Indicating syndrome types: Dahuoluodan mainly treats the syndrome of qi and blood deficien.

    Most of the qi and blood deficiency types are swelling and pain of muscles, bones and joints or less swelling and pain, pale complexion, fatigue, shortness of breath, e.

    Spontaneous sweating, heart palpitations, lack of food and loose stools, pale red tongue with insufficient lubrication, yellow or thin white fur, and a deep and slow pul.

    Governance is mainly based on nourishing qi and nourishing blood, soothing meridians and activating collatera.

    Modern pharmacological research : Studies have shown that Dahuoluodan can improve the phagocytic ability of mononuclear macrophages in mice, enhance the immune ability of the body, and inhibit the otitis caused by xylene and formaldehyde in mi.

    The inflammatory reaction of the hind toes of rats has a good anti-inflammatory effect, can improve the pain threshold of mice to electrical stimulation, and has a certain analgesic effe.

    Modern Pharmacological Research Modern Pharmacological Research : Research: Studies have shown that Dahuoluodan can improve the phagocytic ability of mononuclear macrophages in mice, and has the effect of enhancing the body's immune abili.

    Mouse otitis and formaldehyde-induced inflammation of the hind toes of rats have a good anti-inflammatory effect, can improve the pain threshold of mice to electrical stimulation, and have a certain analgesic effe.

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