 Home > Active Ingredient News > Immunology News > A&R: IgG anti-citrullinated protein antibody variable domain glycosylation increases before the onset of rheumatoid arthritis and stabilizes thereafter

A&R: IgG anti-citrullinated protein antibody variable domain glycosylation increases before the onset of rheumatoid arthritis and stabilizes thereafter

 Last Update: 2022-08-15
 Source: Internet
 Author: User

Tags

jo 1 antibody

gelato domain

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

OBJECTIVE: Autoimmune responses in rheumatoid arthritis (RA) are marked by the presence of anti-citrullinated protein antibodies (ACPA.

The autoimmune response in rheumatoid arthritis (RA) is marked by the presence of anti-citrullinated protein antibodies (ACPA.

Methods: We analyzed IgG ACPA VDG profiles from seven different cohorts from Japan, Canada, the Netherlands, and Sweden using liquid chromatograph.

The researchers analyzed IgG ACPA VDG profiles from seven different cohorts from Japan, Canada, the Netherlands, and Sweden using liquid chromatograph.

IgG ACPA VDG was significantly increased at disease onset ( P < 0001 ) and was associated with pre-diagnostic ACPA levels and epitope sprea.

The abundance of IgG ACPA VDG increases with RA onset and correlates with the maturity of the ACPA respons.

Source: after Kissel T, Hafkenscheid L, Wesemael TJ, et .
IgG Anti-Citrullinated Protein Antibody Variable Domain Glycosylation Increases Before the Onset of Rheumatoid Arthritis and Stabilizes: A Cross-Sectional Study Encompassing ~1,500 Sampl.
Arthritis Rheumat.
2022 Jul; 74(7):1147-115 doi: 11002/a.
4209 Epub 2022 May 2 PMID: 3518871 Leave a comment here

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

Tracheal cytotoxin.

CAS No.: 94102-64-4

Industrial Grade

$10000/G FOB

Factory Supply LL 37 CAS 154947-66-7 LL-37 peptide raw powder

CAS No.: 154947-66-7

Pharmacy Grade

$13-16/UNIT FOB

Inosine pranobex 36703-88-5

CAS No.: 36703-88-5

Pharmaceutical Grade

$100/KG EXW

Hot Tags

jobs united states(236)

united states jobs(223)

1 year treasury(277)

1 year subscription(296)

single use technology(195)

announcements today(81)

ups united states(221)

united states logo(227)

80 20 company(94)

healthy food name(42)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.