A&R: Tumor necrosis factor inhibitor therapy is associated with a time-shifted delay in radiographic sacroiliitis progression in patients with axial spondyloarthritis

OBJECTIVE: Over the years , research on structural damage in axial spondyloarthritis (axSpA) has focused on assessing radiographic spinal progression as one of the main determinants of function and spinal mobility

Research on structural injury for many years has focused on assessing radiographic spinal progression as one of the main factors in determining function and spinal mobility

We included patients from the German spondyloarthritis initial cohort who had at least one sacroiliac joint radiograph at baseline and during follow - up

In total, 301 axSpA patients ( 166 non-imaging [nr-axSpA] and 135 radiographic [r-axSpA] ) contributed 737 imaging intervals .

TNFi is associated with a reduction in radiographic sacroiliitis progression in axSpA patients .

 

Source:

Source:

Torgutalp, M.

Torgutalp, M.
, Rios Rodriguez, V.
, Proft, F.
, Protopopov, M.
, Verba, M.
, Rademacher, J.
, Haibel, H.
, Sieper, J.
, Rudwaleit, M.
and Poddubnyy, D.
(2022), Treatment with Tumour Necrosis Factor Inhibitors is Associated with a Time-Shifted Retardation of Radiographic Sacroiliitis Progression in Patients with Axial Spondyloarthritis: 10-year Results from the German Spondyloarthritis Inception Cohort.
Arthritis Rheumatol.
Accepted Author Manuscript.
  https:// doi.
org/10.
1002/art.
42144 https://doi.
org/10.
1002/art.
42144

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