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AJG: In adults with eosinophilic esophagitis, treatment adherence is worse in younger patients?

 Last Update: 2022-11-01
 Source: Internet
 Author: User

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An article published in the American Journal of Gastroenterology (AJG) examined adherence to prescription medications and dietary maintenance therapy in adults with eosinophilic esophagitis (EoE) and analyzed the influencing factors
.

This cross-sectional study included adult patients
with EoE receiving medication or dietary maintenance therapy.
Patients are asked to complete questionnaires about:

Treatment adherence: Medication Adherence Rating Scale
Therapeutic beliefs: Beliefs about Medicine Questionnaire
Disease Beliefs: Disease Perception Questionnaire
Current symptoms: Straumann dysphagia index

The study included

a total of 177 patients with EoE (71% male), with a median age of 43 years
.

The proportion of patients with poor treatment adherence (medication adherence rating scale < 21 or dietary adherence rating scale < 21) was higher in this study cohort, at 41.
8%.

Patients treated with medication appeared to have poorer adherence compared with those treated with diet (35.
1 versus 41.
8 percent, P = 0.
320).

Multivariate logistic regression analysis identified the following independent factors associated with poor treatment adherence:

Age < 40 years (OR 2.
571, 95% CI 1.
195 to 5.
532, P=0.
016).
The duration of the disease (years) was longer (OR 1.
130, 95% CI 1.
014-1.
258, P=0.
027).
Symptoms were severe (Straumann dysphagia index) (OR 1.
167, 95% CI 1.
012 to 1.
345, P=0.
034).
Low necessity beliefs (OR 4.
423, 95% CI 2.
169-9.
016, P < 0.
001).

discuss

Most adult patients with EoE have poor
adherence to maintenance therapy.
Clinicians should pay more attention to this during treatment, especially for younger patients, and discuss the need for
treatment.

References: Haasnoot M L, Safi S, Bredenoord A J.
Poor Adherence to Medical and Dietary Treatments in Adult Patients With Eosinophilic Esophagitis[J].
The American Journal of Gastroenterology, 2022, 117(9): 1412-1418.

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