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    Home > Active Ingredient News > Digestive System Information > AJG: Postoperative endoscopic recurrence of the new end-end rectum rather than the postoperative endoscopic recurrence of the matching mouth is the main cause of long-term results of Crohn's disease.

    AJG: Postoperative endoscopic recurrence of the new end-end rectum rather than the postoperative endoscopic recurrence of the matching mouth is the main cause of long-term results of Crohn's disease.

    • Last Update: 2020-10-12
    • Source: Internet
    • Author: User
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    BACKGROUND: Early colonoscopy in the first year after surgery is the gold standard for evaluating postoperative recurrence in patients with Crohn's disease (CD) with a return colonectomy.
    the purpose of the study was to assess the relationship between the presence and severity and long-term prognosis of lip and rectal lesions in early postoperative colonoscopy.
    : The researchers conducted a forward-looking multi-center study.
    to include CD patients undergoing back or colon surgery in this study.
    a colonoscopy six months after surgery on all patients to determine the condition of the mouth and new end of the relegation.
    endoscope scores that matched oral and intestinal lesions, respectively.
    clinical recurrence is defined by CD-related symptoms and confirmed by imaging and endoscopy;
    results: 193 out of 225 patients received long-term follow-up (medium follow-up time: 3.82 years).
    the median clinical recurrence was 47.6 months.
    compared with patients without reental lesions (I(0),), patients with endoscopic endoscopy after surgery, regardless of their severity (I(1) or I (2,3,4),), their clinical recurrence period was significantly shortened (I(0)vs I (2,3,4):P s 0.0003; I(0)vs I (1):P s 0.0008 and I (1) vs I (2,3,4):P s 0.43).
    patients with only enteric lesions had better clinical long-term outcomes than patients with only rectal lesions (P - 0.009).
    Conclusion: A relapse score of the matching mouth and the new end of the relent after surgery can provide a more accurate estimate of postoperative recurrence of CD, and the researchers also found that patients with relent lesions could benefit from treatment to improve long-term prognosis.
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