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Juvenile iron deficiency anemia is related to menstrual bleeding (HMB) and bleeding disorders (BD).
Although data on predictors of bipolar disorder in adolescent HMB patients are emerging, it is not clear whether iron deficiency without anemia is associated with bipolar disorder in adolescents.
Phase disorders are related, and the threshold of ferritin associated with HMB fatigue in adolescents is unclear
.
Therefore, in a multicenter study, the research team recruited HMB adolescents without bipolar disorder
.
Participants were tested for bipolar disorder and anemia at the Young Women's Hematology Clinic, and completed the PedsQLTM Fatigue Scale
Von Willebrand Disease, Platelet Function Deficiency, Clotting Factor Deficiency, and Hyperactivity Syndrome 250
All participants underwent laboratory tests including complete blood count and serum ferritin
.
Prothrombin time, activated partial thrombin time, fibrinogen and VWD panel tests were performed on all participants
Among them, 43% (95% confidence interval: 36-50%) were diagnosed as bipolar disorder
.
61% (n=119) had serum ferritin levels <15ng/mL; 23.
Low ferritin two-class classification <15 or ≥15ng/mL is not related to bipolar disorder (p=0.
The study shows that iron deficiency and fatigue are common in adolescents with bipolar disorder.
Zia A,Stanek J,Christian-Rancy M,et al.
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