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American Journal of Nutrition: Consumption of dairy products may reduce the risk of type 2 diabetes

 Last Update: 2021-07-30
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Epidemiological studies have found that there is a moderate inverse association between the consumption of dairy products and the risk of type 2 diabetes (T2D)
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Whether the plasma metabolite profile associated with dairy consumption reflects this relationship remains unclear

Epidemiological studies have found that there is a moderate inverse association between the consumption of dairy products and the risk of type 2 diabetes (T2D)

The Jean-Philippe Drouin-Chartier team published an article in the American Journal of Nutrition, studying and analyzing the plasma metabolites related to the total consumption of dairy products and specific consumption, and evaluating the relationship between the determined multi-metabolite profile and T2D

1833 participants in the PREDIMED trial were recruited
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The confirmatory cohort included 1,522 pre-test participants in the first year of the trial and 4,932 participants from the Nurses’ Health Study (NHS), Nurses’ Health Study II (NHSII), and a US-based follow-up study of health professionals

1833 participants in the PREDIMED trial were recruited

Graph of regression coefficients for all unique metabolites associated with the consumption of each dairy product category identified in the PREDIMED baseline discovery cohort
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The total intake of dairy products is related to 38 metabolites
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C14:0 sphingomyelin (positive coefficient), c34:0 phosphatidylethanolamine (positive coefficient) and γ-butyl betaine (negative coefficient) are positively correlated with the total consumption and specific consumption of dairy products

The total intake of dairy products is related to 38 metabolites

In summary, the total intake of dairy products is related to 38 metabolites, of which 3 metabolites are consistent with the subtypes of dairy products (c14:0 sphingomyelin, c34:0 phosphatidylethanolamine, γ-butyl betaine)

Jean-Philippe Drouin-Chartier, Pablo Hernández-Alonso, Marta Guasch-Ferré, Miguel Ruiz-Canela, Jun Li, Clemens Wittenbecher, Cristina Razquin, Estefanía Toledo, Courtney Dennis, Dolores Corella, Ramon Estruch, Montserrat Fiten, A Deirdre K Tobias, Alberto Ascherio, Lorelei A Mucci, Kathryn M Rexrode, Elizabeth W Karlson, Karen H Costenbader, Charles S Fuchs, Liming Liang, Clary B Clish, Miguel A Martínez-González, Jordi Salas-Salvadó, Frank B Hu, Dairy consumption, plasma metabolites, and risk of type 2 diabetes,The American Journal of Clinical Nutrition , Volume 114, Issue 1, July 2021, Pages 163–174,https://doi.

Jean-Philippe Drouin-Chartier, Pablo Hernández-Alonso, Marta Guasch-Ferré, Miguel Ruiz-Canela, Jun Li, Clemens Wittenbecher, Cristina Razquin, Estefanía Toledo, Courtney Dennis, Dolores Corella, Ramon Estruch, Montserrat Fiten, A Deirdre K Tobias, Alberto Ascherio, Lorelei A Mucci, Kathryn M Rexrode, Elizabeth W Karlson, Karen H Costenbader, Charles S Fuchs, Liming Liang, Clary B Clish, Miguel A Martínez-González, Jordi Salas-Salvadó, Frank B Hu, Dairy consumption, Plasma metabolites, and Risk of type 2 Diabetes,of the American Journal of Clinical Nutrition https://doi.
org/10.
1093/ajcn/nqab047 https://doi.
org/10.
1093/ajcn/nqab047 in this message

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