echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Blood System > And Platinum Pharmaceuticals completed the B-plus round of financing of $75 million and C round of financing of $100 million, at the Cell Engager Summit to show its BCMAxCD3 dual specific antibodies.

    And Platinum Pharmaceuticals completed the B-plus round of financing of $75 million and C round of financing of $100 million, at the Cell Engager Summit to show its BCMAxCD3 dual specific antibodies.

    • Last Update: 2020-09-22
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com
    Founded in December 2016, Harbor BioMed has grown rapidly, completing $75 million in B-plus financing and $102.8 million in round C financing this year.
    recent Hong Kong IPO prospectos were also made public, spending $15.2m on research and development in the first half of this year.
    Photo Source: and Platinum Pharmaceuticals Prospectine Source: And Platinum Pharmaceuticals Prospects at Cell Engager Summit 2020, and Platinum Pharmaceuticals showcasing its new dual-specific antibody BCMAxCD3 (HBM7020).
    HBM7020 is based on its HBICETM platform and has significant tumor lethality and minimal cytokine response, which can be converted into relatively effective and safe treatments.
    B cell mature antigen (BCMA) is a highly expressed surface marker on malignant plasma cells in patients with multiple myeloma (MM) and has been recognized as an ideal target for T-cell redirect therapy.
    currently, treatments for BCMA are still unresponsive and relapsed in some patients. limitations such as fast, toxicity caused by cytokine release syndrome (CRS) and short half-life.
    HBM7020 can overcome certain limitations and become a new generation therapy for multiple myeloma, selectively removing BCMA-positive MM cells with less cytokine release.
    HBM7020 is designed in the form of a "2-plus", with an anti-CD3 binding domain used to activate T-cell activity and two anti-BCMA binding domains to improve the selectivity of BCMA-positive MM cells.
    compared to rival Regeneron's BCMAxCD3 dual-specific antibodies, HBM7020 effectively kills BCMA-positive MM cells and reduces the risk of CRS (cytokine release syndrome).
    BCMAxCD3 dual-specific antibody for regenerative cells (Image Source: Guangming)
    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.