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Ann Transl Med: analysis of m6A-related features associated with the tumor immune microenvironment and prediction of survival in acute myeloid leukemia

 Last Update: 2022-09-30
 Source: Internet
 Author: User

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Most previous research has focused on the intrinsic carcinogenic pathway of tumors
.

The research team extracted data from the Cancer Genome Atlas (TCGA) database, including RNA-sequencing (RNA-seq) transcriptome data and data on the corresponding clinical features of
AML patients.

Figure 1: 5 M6A-related markers
of differentially expressed genes between AML patients and normal individuals.

The research team identified 2 molecular subtypes (clusters 1 and 2) by consistent clustering of important m6A regulators in AML
.

Overall, this study illuminates the important role
of m6A methylation in AML time.

Original Source:

Yuan S, Cong Z, Ji J, Zhu L, Jiang Q, Zhou Y, Shen Q, Damiani D, Xu X, Li B.

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