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Introduction: Recently, a study published in the journal JAMA Surgery showed that obese patients who have lost a lot of weight after undergoing metabolic surgery have a significantly lower risk of serious complications of COVID-19
.
Study Overview Participants from the same center in the United States, the number of nearly 12,000, during the median follow-up period of the past 8 years, the weight of obese patients undergoing metabolic surgery was reduced by an average of nearly 19% compared with control obese patients who did not undergo surgery
.
During the 12-month period from March 1, 2020 to March 1, 2021, the researchers evaluated the COVID-19 status of 2,958 surgical group and 8,851 control participants
.
During the period, 206 participants in the surgery group and 578 participants in the control group were infected with COVID-19.
At the time of the positive diagnosis, the average weight of the participants in the surgery group was 108.
4 kg and the control group was 128.
4 kg
.
Although the infection rate is similar, the risk of severe illness is significantly reduced.
The results of the study show that the incidence of COVID-19 in the operation group and the control group is roughly the same.
The infection rate in both groups from March 2020 to March 2021 is about 9%
.
However, in the surgery group, the risk of hospitalization was reduced by 49%, the risk of additional oxygen was reduced by 63%, and the risk of severe COVID-19 was reduced by 60%
.
In addition, the all-cause mortality in the surgery group was reduced by 73%, although this difference was not significant (P=0.
09)
.
Obesity is a "changeable risk factor" for severe COVID-19.
Some scholars said that it is usually difficult to design a special team-controlled trial for severely obese patients to evaluate the results of new coronary pneumonia after weight loss intervention
.
The data of this study provides good evidence that substantial and sustained weight loss can reduce the risk of severe COVID-19 in infected obese people
.
Although the risk of infection is the same, among those who have undergone metabolic surgery and subsequent weight loss, the incidence of complications is much lower
.
References: Aminian A, Tu C, Milinovich A, Wolski KE, Kattan MW, Nissen SE.
Association of Weight Loss Achieved Through Metabolic Surgery With Risk and Severity of COVID-19 Infection Published.
JAMA Surg.
online December 29, 2021.
doi :10.
1001/jamasurg.
2021.
6496