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    Home > Active Ingredient News > Immunology News > Arthritis Rheumatol: Differences in oral microbes between patients with rheumatoid arthritis and healthy people

    Arthritis Rheumatol: Differences in oral microbes between patients with rheumatoid arthritis and healthy people

    • Last Update: 2021-12-02
    • Source: Internet
    • Author: User
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    Although genetic factors have a clear impact on rheumatoid arthritis (RA), environmental factors also play a very important role



    The study recruited three groups of subjects (50 in each group): 1) early RA patients (in line with the 2010 classification criteria of the American College of Rheumatology/European Rheumatology Association), 2) individuals at risk of developing RA (arthralgia) Patients, RA-related autoantibodies are positive), and 3) healthy controls


    There were no significant differences in the three periodontal indicators of early RA patients, high-risk individuals, and healthy controls (BOP P = 0.


    The results showed that there were significant differences in the microbial composition of saliva (F=2.



    Comparison of the relative abundance of oral microbes among the three groups

    It can be seen that compared with healthy controls, the oral microbiomes of early RA patients and RA high-risk individuals are similar, and the oral microbiota of the two is characterized by an increased relative abundance of potential pro-inflammatory bacteria


    The characteristic of both oral microbes is the increased relative abundance of potential pro-inflammatory bacteria


    Original source:

    Original source:

    Johanna M.


     



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