Autoimmune diseases, increase the risk of cardiovascular disease! Lancet Journal Study 2.5 million people

Recently, a data analysis of 2.

The study included 446,449 patients with autoimmune diseases (9.

During the median follow-up period of 6.

The incidence of cardiovascular disease in patients with autoimmune diseases was 23.

Further analysis showed that the risk of cardiovascular disease increased with the increase of the types of autoimmune diseases: the cardiovascular risk of one disease, 2 diseases and ≥ 2 diseases increased by 41%, 1.

In sensitivity analysis, correction for traditional cardiovascular risk factors such as blood pressure, smoking, obesity, cholesterol, and type 2 diabetes reduced the risk
associated with autoimmune diseases only slightly.

The researchers analyzed that inflammation, especially chronic inflammation, is a common pathophysiological mechanism
of many cardiovascular diseases.

Autoimmune diseases, such as rheumatoid arthritis, are associated
with increased cardiovascular morbidity and mortality.

Source: Conrad N, Verbeke G, Molenberghs G,et al.