BJH: Persistent fatigue symptoms, neuropathy, and role dysfunction in survivors of indolent non-Hodgkin lymphoma: a longitudinal PROFILES registry study

Little is known about long-term health-related quality of life (HRQoL) and symptom persistence in patients with indolent non-Hodgkin lymphoma (iNHL) .

Little is known about long-term health-related quality of life (HRQoL) and symptom persistence in patients with indolent non-Hodgkin lymphoma (iNHL) .

Figure 1: Flow chart of the data acquisition process

Figure 1: Flow chart of the data acquisition process

The study included longitudinal surveys of patients diagnosed between 1999 and 2014 and four or more months after diagnosis

Table 1: Patient characteristics by cancer type or normal population mean (SD) or N (%)

Table 1: Patient characteristics by cancer type or normal population mean (SD) or N (%) Table 1: Patient characteristics by cancer type or normal population mean (SD) or N (%)

Initial treatment was active surveillance (52%), systemic therapy (31%), or radiotherapy (13%)

Initial treatment was active surveillance (52%), systemic therapy (31%), or radiotherapy (13%)

Figure 2: (A) Fatigue; (B) Neuropathy; and (C) Role Function 10 years after diagnosis

Figure 2: (A) Fatigue; (B) Neuropathy; and (C) Role Function 10 years after diagnosis

Figure 3: Percentage of patients with persistent fatigue, neuropathy, and role dysfunction compared to the normal population

Figure 3: Percentage of patients with persistent fatigue, neuropathy, and role dysfunction compared to the normal population

Scores remained relatively stable with no clinically relevant changes for up to 10 years after diagnosis

 

Original source:

Original source:

Ekels, A ,van de Poll-Franse, LV ,Posthuma, EFM ,Kieffer, J ,Issa, DE ,  Koster, A , et al.

Ekels, A ,  van de Poll-Franse, LV ,  Posthuma, EFM ,  Kieffer, J ,  Issa, DE ,  Koster, A , et al.
  Persistent symptoms of fatigue, neuropathy and role-functioning impairment among indolent non-Hodgkin lymphoma survivors: A longitudinal PROFILES registry study .
  Br J Haematol .
  2022 ;  00 :  1–12 .
https://doi.
org/10.
1111/bjh.
18139 Ekels , A ,  van  de Poll-Franse, LV ,  Posthuma, EFM ,  Kieffer, J ,  Issa, DE ,  Koster, A, et al.
  Persistent symptoms of fatigue, neuropathy and role-functioning impairment among indolent non-Hodgkin lymphoma survivors: A longitudinal PROFILES registry study .
Br  J Haematol .
  2022 ;  00 :  1–12.
https :  //doi.
org/10.
1111 /bjh.
18139 Ekels, A van de Poll-Franse, LV Posthuma, EFM Kieffer, J Issa, DE Koster, A Persistent symptoms of fatigue, neuropathy and role-functioning impairment among indolent non-Hodgkin lymphoma survivors: A longitudinal PROFILES registry study Br J Haematol 2022 00 1 12

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