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Blood Adv: risk of thrombosis in adults with D-dimer and newly diagnosed acute lymphoblastic leukemia

 Last Update: 2022-10-12
 Source: Internet
 Author: User

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Patients with acute lymphoblastic leukemia (ALL) are at increased risk of thrombosis and/or bleeding events during early chemotherapy, particularly when

Therefore, a research team attempted to conduct a retrospective cohort study at the University of Chicago to examine D-dimers as biomarkers

Figure 1: Cumulative incidence

In patients with D-dimer (≥ 4 μg/mL), the 100-day cumulative incidence of venous or arterial thrombosis (95% CI [CI]) was 52.

Figure 2: ROC curve

When testing for potential confounders in a range of binary logistic regression models, the association between D-dimer and thrombosis persisted

In summary, D-dimer levels at the time of all diagnoses are associated with venous or arterial thrombosis over

Original Source:

Anderson DR, Stock W, Karrison TG, Leader A.

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