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Blood: Small residual lesions predict prognosis in patients with mantle cell lymphoma in real time

 Last Update: 2022-10-12
 Source: Internet
 Author: User

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Prognosis in young patients with mantle cell lymphoma (MCL) has improved

Minimal residual lesion (MRD) analysis is a known prognostic prediction tool

Of the 300 patients enrolled, 250 (83%) all carried a molecular marker, allowing us to analyze

ASCT induced polymer remission (91% in peripheral blood and 83% in bone marrow).

To improve MRD performance, the researchers developed a time-changing model based on regularly updated MRD results and MIPI (International Prognostic Index for Mantle Cell Lymphoma), which showed an area of up to 0.

In summary, MRD is a strong predictor throughout the natural history of MCL, applicable to models

Original Source:

Simone Ferrero, Daniele Grimaldi, Elisa Genuardi, et al.

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