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    Home > Active Ingredient News > Digestive System Information > BMC Gastroenterology: Ustekinumab trough concentrations predict endoscopic response in patients with Crohn's disease

    BMC Gastroenterology: Ustekinumab trough concentrations predict endoscopic response in patients with Crohn's disease

    • Last Update: 2022-05-11
    • Source: Internet
    • Author: User
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    Crohn's disease (CD) is an inflammatory bowel disease (IBD) characterized by clinical symptoms such as abdominal pain, chronic diarrhea, gastrointestinal bleeding, and intestinal complications such as strictures and fistulas, although the exact pathogenesis of CD remains unclear.


    Crohn's disease (CD) is an inflammatory bowel disease (IBD) characterized by clinical symptoms such as abdominal pain, chronic diarrhea, gastrointestinal bleeding, and intestinal complications such as strictures and fistulas, although the exact pathogenesis of CD remains unclear.


     

    The results showed that endoscopic activity was negatively correlated with serum UST trough levels (Spearman's rank correlation coefficient (ρ) = -0.


     

    This study demonstrated that increased endoscopic activity was significantly associated with lower UST trough levels and serum albumin levels


    This study demonstrated that increased endoscopic activity was significantly associated with lower UST trough levels and serum albumin levels


    Original source:

    Hisashi Hirayama.


    Hisashi Hirayama.
    Et al.
    Ustekinumab trough levels predicting laboratory and endoscopic remission in patients with Crohn's disease.
    BMC Gastroenterology.
    2022.
    Ustekinumab trough levels predicting laboratory and endoscopic remission in patients with Crohn's disease.


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