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Executive summary
.
status quo
likely to develop this condition than men.
This is partly due to a decrease in estrogen levels after menopause, resulting in loss
of trabecular and cortical bone mineral density.
With age, estrogen deficiency leads to an increase in inflammatory mediators, further enhancing bone resorption and inhibiting bone formation
.
Study co-author Dr.
Connie Rogers, a professor in the Department of Nutritional Sciences at the University of Georgia, said
- There is evidence of an association between chronic inflammation and osteoporosis and fracture risk, and this study explored the relationship between inflammation and bone biomarkers by looking at postmenopausal women, as well as the effects
of dietary interventions.
conclusion
of 50g/day (5-6 prunes per day) and 100g/day (10-12 prunes per day) on volumetric bone density (vBMD) and bone geometry.
The results found that higher levels of inflammatory markers were associated with lower trabecular scores in the lumbar vertebrae among study participants, meaning that
the more inflammation, the worse the bone health;
The estimated intensity strain index (SSI) of the control group and the prune intervention group was evaluated at 14% of the tibial backbone and found that the SSI of the control group decreased within 12 months, while the SSI of the two prune intervention groups did not change significantly;
Total vBMD was evaluated at 38% of the tibial backbone, and the total vBMD decreased in the control group at 12 months, but there was no trend towards reduction in the prune intervention group;
Consuming 5-6 prunes per day can maintain vBMD of the total hip and tibia, a finding that appeared at 6 months and lasted until the 12th month; Consuming 10-12 prunes per day can also maintain vBMD
.
Meaning prunes can help prevent bone loss
.
prospect
Rogers said: "
This study shows that inflammatory markers are negatively correlated with bone health in postmenopausal women, suggesting that inflammation may be an important mediator of postmenopausal bone loss and a potential target for nutritional therapy;
The group of women who consumed prunes experienced some bone benefits by maintaining SSI and vBMD of their hips and tibia, and dietary interventions to maintain bone health
could be considered in the future.
Comment debut: EurekAlert!
Media Contact：
Kiaran Locy
California Prune Board
klocy@californiaprunes.
org
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