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Coronary artery disease (CAD) has an extremely high incidence in diabetic patients and is the leading cause of death in diabetic patients
This study aimed to investigate how CAD affects left ventricular systolic and diastolic function in patients with T2DM
A total of 282 T2DM patients (104 with CAD [CAD+] and 178 without CAD [CAD-]) and 83 sex- and age-matched healthy controls were recruited for cardiac MRI
Cardiac parameters of the three groups of subjects
Cardiac parameters of the three groups of subjectsCompared with healthy controls, patients with T2DM (CAD-) had increased left ventricular end-diastolic and end-systolic volume indices and decreased overall left ventricular strain; whereas patients with T2DM (CAD+) had significantly higher LV end-diastolic and end-systolic volume indices compared with T2DM (CAD-) and healthy controls.
Compared with healthy controls, patients with T2DM (CAD-) had increased left ventricular end-diastolic and end-systolic volume indices and decreased overall left ventricular strain; whereas patients with T2DM (CAD+) had significantly higher LV end-diastolic and end-systolic volume indices compared with T2DM (CAD-) and healthy controls.
Effects of CAD on left ventricular systolic and diastolic function in patients with T2DM
Effects of CAD on left ventricular systolic and diastolic function in patients with T2DMFrom patients with Gensini score ≤60, to patients with Gensini score >60, all parameters of LV global resiliency, except PDSR-L, showed a gradual decrease from normal controls (all p<0.
From patients with Gensini score ≤60, to patients with Gensini score >60, all parameters of LV global resiliency, except PDSR-L, showed a gradual decrease from normal controls (all p<0.
Coronary artery disease has an additional deleterious effect on left ventricular systolic and diastolic function in patients with type 2 diabetes
Original source:
Original source:Wang, J.
The adverse impact of coronary artery disease on left ventricle systolic and diastolic function in patients with type 2 diabetes mellitus: a 3.
0T CMR
study
