Cardiovasc Diabetol: Effect of Lipid Variability on Mortality of Type 2 Diabetes

In the past 30 years, the prevalence of diabetes has increased significantly, and this situation has placed a huge burden on the healthcare system
.

Diabetes the heart vascular risk disease (CVD) increased by an average twice, earlier onset diabetes, the higher the mortality rate, mainly due to cardiovascular disease mortality

Diabetic blood vessels

Dyslipidemia is the main cardiovascular risk factor and is common in diabetic patients
.

Most guidelines focus on optimal blood lipid levels and rarely discuss changes in blood lipid profiles

guide

The researchers screened a total of 10,583 type 2 diabetes patients aged 30 years and older who participated in the diabetes management plan and followed up for 3 years or more
.

Use the coefficient of variation to calculate the variability of the lipid profile within 3 years after entering the management plan

manage

The correlation between the variability of blood lipids and the risk ratio of death

The correlation between the variability of blood lipids and the risk ratio of death

After an average follow-up of 6.
4 years, a total of 1838 all-cause deaths (including 809 cardiovascular deaths) were recorded
.

For every 10% increase in the variability of high-density lipoprotein cholesterol , low -density lipoprotein cholesterol , and total cholesterol, the risk ratios of all-cause death are 1.

For every 10% increase in the variability of high-density lipoprotein cholesterol , low -density lipoprotein cholesterol , and total cholesterol, the risk ratios of all-cause death are 1.

In summary, in addition to triglyceride variation, blood lipid variation is closely related to all-cause mortality and cardiovascular mortality in patients with type 2 diabetes

In addition to triglyceride variants, blood lipid variants are closely related to all-cause mortality and cardiovascular mortality in patients with type 2 diabetes.

Original source:

Wang, MC.

Leave a message here