Cardiovascular health is key to reducing the risk of Alzheimer's disease

Source: Harvard. In a recent study published in plos medicine, edu found that atherosclerosis is not only associated with cardiovascular disease, but is also a risk factor for cognitive decline and dementia, and that maintaining heart health can help delay or prevent Alzheimer's disease.
nearly 50 million people worldwide now suffer from dementia, and the number of people with dementia is expected to triple by 2050 as society ages.
there is still no effective clinical treatment for dementia, so prevention is still key!" Associations between arterial stiffening and brain structure, perfusion, and cognition in the Whitehall II Imaging Sub-study: A retrospective cohort study doi: 10.1371/journal.pmed.1003467 The cardiovascular system has many blood vessels, and the arteries are the blood vessels that take blood out of the heart.
arteriosclerosis is a non-inflammatory lesion of arteries, which thickens, hardens, loses elasticity, narrows the tube cavity, and makes the blood flow poor, so that the blood is more viscous than normal blood and contains clots.
these factors, arteries can be blocked.
the study, researchers included 542 participants (with an average age of 63.9 years) who received 30 years of clinical follow-up.
study, aortic pulse wave velocity (PWV) was used as a measure of aortic stiffness.
participants were measured twice for aortic sclerosis at the age of 64 and 68.
at an average age of 69, they underwent cognitive tests and MRI scans to assess the size, connections, blood supply and cognitive abilities of participants in different brain regions.
In an MRI scan, the researchers assessed gray mass (GM) volume, white mass (WM) microstructage, white lesions (WMLs) and cerebral blood flow (CBF), and in cognitive tests, they assessed participants' memory, language fluency, and executive function.
study found that in the middle and late years, the faster aortic hardening was associated with poorer WM microstructile integrity, lower blood flow, and poor brain connectivity markers.
baseline aortic hardening was negatively associated with memory, language fluency, and speech learning outcomes.
The association between aortic pulse wave velocity and brain structure and cognitive outcomes between aortic sclerosis and the association between WM microstructage and CBF pulse wave velocity and brain and cognitive outcomes so that accelerated aortic hardening in middle age may affect brain health, especially the connectivity between fragile blood vessels in the brain and different brains, increasing the risk of Alzheimer's disease.
study shows that preventing and treating atherosclerosis earlier in a person's life can provide cognitive benefits in older adults and help delay the onset of dementia.
are vascular diseases that occur with age, most commonly in middle-aged and older people over the age of 40.
previously thought that atherosclerosis progressed faster after the age of 49, but a 2020 study published in the Journal of the American College of Cardiology found that the process of atherosclerosis begins to accelerate in healthy people from the age of 40.
in just three years of follow-up, 40 percent of healthy people between the ages of 40 and 50 experienced atherosclerosis in different locations, including cervical arteries, arteries, coronary arteries, etc.
atherosclerosis is getting younger and younger, how can we prevent it? The most important causes of arteriosclerosis are high blood pressure, hyperlipidemia and smoking.
, high-risk factors such as hypertension are most likely to be overlooked in middle-aged and young people.
young people, many people do not realize that they have high blood pressure, and do not receive timely treatment.
in the past, high blood pressure is thought to be an exclusive disease of the elderly and does not seem to be related to young people.
, however, a growing body of research suggests that high blood pressure is "younger."
" A recent cross-sectional study published in jama sub-journal JAMA Network Open analyzed the incidence and awareness of hypertension in 898,929 subjects between the ages of 35 and 49, and found that 26.2% of young and middle-aged subjects had high blood pressure, and that most untreated hypertension patients were unaware of their high blood pressure.
simple systolic hypertension (ISH): systolic blood pressure level ≥140mmHg, thystolic pressure level <90mmHg< Zhang pressure level ≥90mmHg; systolic hypertension (SDH): systolic blood pressure level ≥140mmHg, thystolic pressure level ≥90mmHg;
even more surprising was that 86.7 per cent of young and middle-aged ISH patients did not receive treatment, while 85.7 per cent of young and middle-aged IDH and 75.1 per cent did not receive the corresponding interventions, respectively.
the prevalence of ISH patients of different ages, the study also found that the majority of untreated hypertension patients are not actually aware of their own hypertension, only 6.8% of ISH, 5.7% of IDH and 17.7% of SDH patients have a better understanding of their own hypertension.
the study, which looked at ISH among participants of all ages and blood pressure levels, found that about a quarter of young people had high blood pressure and were less likely to know and control it.
high blood pressure is a high risk factor for atherosclerosis, so we have to pay attention to our own blood pressure.
we should check our blood pressure levels regularly after the age of 35.
in addition to paying attention to their own hypertension, in daily life we can also follow the following 5 points to prevent atherosclerosis.
1, eat a reasonable diet: reduce saturated fatty acids and sugar intake, eat more vegetables, especially cruciate trophies vegetables, such as curly orchids, cabbage and purple kale.
2, moderate movement and stretching: Stretching can soften blood vessels to some extent, thus preventing arteriosclerosis.
3, weight control: generally to body mass index (BMI) 20 to 24 normal weight, or waist circumference as the standard, generally not more than 80cm female, male waist circumference not more than 85cm standard.
4, Quit Smoking and Alcohol: Smoking is a high risk factor for atherosclerosis.
5, avoid staying up late: lack of sleep can lead to the formation of fatty arterial plaques, or atherosclerosis.
, controlling blood pressure and preventing arterial vascular disease not only prevent stroke, myocardial infarction and heart attack, but also help prevent Alzheimer's disease.
young to take good care of their own body, pay attention to their blood pressure and cardiovascular health, so that in old age, will not be plagued by disease.
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