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CELL HOST MICROBE: What are the microbiomes involved in early colorectal cancer?

 Last Update: 2021-09-28
 Source: Internet
 Author: User

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Colorectal cancer (CRC) is a common type of cancer that begins with a precursor lesion called a polyp in the colon, and its development time spans several years

The intestine is colonized by approximately 1014 bacteria, which is called the microbiota, which is the basis of human health and development

Changes in the microbiota are related to colorectal polyps, and specific microbial species have been identified as possible carcinogens .

Bacterial imbalance and enrichment of fragilis in patients with colorectal polyps

Researchers used sequencing and culture techniques to find different microbial characteristics between patients with and without polyps and between polyp subtypes

There is a correlation between the recovered Bacteroides fragilis and the levels of inflammatory cytokines in the mucosa near the polyps.

Original source:

Melissa C.

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