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    Home > Biochemistry News > Biotechnology News > Cell publication reveals the secret behind the threat of non-alcoholic liver disease

    Cell publication reveals the secret behind the threat of non-alcoholic liver disease

    • Last Update: 2021-07-31
    • Source: Internet
    • Author: User
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    Figure: Liver fibrosis section showing red collagen fibers

    Source: Helmholtz Zentrum München / Anne Loft

    Non-alcoholic fatty liver is the most common liver disease in the world, accounting for about 25% of the world's population


    Liver fibrosis is a strong predictor of long-term mortality in patients with non-alcoholic fatty liver


    Loss of identity can lead to dysfunction

    Researchers use comparative genomics to analyze the mechanisms that control the development and special functions of the most abundant cell types in the liver.


    The reprogramming of liver cells is a molecular switch tightly controlled by a protein network, the so-called "transcription factor"


    future career

    Based on these findings, it is now possible to develop new methods to effectively target certain nodes in the protein network to prevent the progression of the disease and even reverse the existing fibrosis, which is currently impossible


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