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The incidence of nonalcoholic fatty liver disease
(NAFLD) in the global adult population is about 25%, and the public health burden caused by it is quite heavy .
Nonalcoholic fatty liver disease can range from steatosis to the more progressive nonalcoholic steatohepatitis (NASH), which can even lead to fibrosis and cirrhosis
The incidence of nonalcoholic fatty liver disease
A total of 129,374 adults aged ≥30 years were enrolled in this study, all of whom participated in a health screening program between 2008 and 2013, were seronegative for HBsAg and anti-HCV antibodies, and had limited daily alcohol consumption (males) <20 g/day,
screening
Elevated liver enzymes were seen in the NAFLD group (n = 21112, 16%) compared to the non-NAFLD group with normal liver enzymes (n = 66801, 51%) and the NAFLD group with normal liver enzymes (n = 41461, 32%) The incidence of both cirrhosis and HCC increased
.
Compared with the non-NAFLD group, the corresponding multivariate adjusted HRs for cirrhosis were 3.
Figure: Elevated liver enzyme levels increase the risk of cirrhosis in patients with nonalcoholic fatty liver disease
This study confirms that individuals with elevated NAFLD and liver enzyme levels have a significantly higher risk of cirrhosis and HCC, which should be considered clinically and should be monitored long-term
.
Original source:
Yu-Han Huang.
Et al.
Influence of Nonalcoholic Fatty Liver Disease with Elevated Liver Enzyme Levels on Risk of Cirrhosis and Hepatocellular Carcinoma.
Clinical Gastroenterology and Hepatology.
2022.
001 kg>2) and non-obese without diabetes ( P <.
05>
Figure: Elevated liver enzyme levels increase the risk of cirrhosis in patients with nonalcoholic fatty liver disease
This study confirms that individuals with elevated NAFLD and liver enzyme levels have a significantly higher risk of cirrhosis and HCC, which should be considered clinically and should be monitored long-term
.
Original source:
Yu-Han Huang.
Et al.
Influence of Nonalcoholic Fatty Liver Disease with Elevated Liver Enzyme Levels on Risk of Cirrhosis and Hepatocellular Carcinoma.
Clinical Gastroenterology and Hepatology.
2022.
05>
Figure: Elevated liver enzyme levels increase the risk of cirrhosis in patients with nonalcoholic fatty liver disease
This study confirms that individuals with elevated NAFLD and liver enzyme levels have a significantly higher risk of cirrhosis and HCC, which should be considered clinically and should be monitored long-term
.
Original source:
Yu-Han Huang.
Et al.
Influence of Nonalcoholic Fatty Liver Disease with Elevated Liver Enzyme Levels on Risk of Cirrhosis and Hepatocellular Carcinoma.
Clinical Gastroenterology and Hepatology.
2022.
Figure: Elevated liver enzyme levels increase the risk of cirrhosis in patients with nonalcoholic fatty liver disease
This study confirms that individuals with elevated NAFLD and liver enzyme levels have a significantly higher risk of cirrhosis and HCC, which should be considered clinically and should be monitored long-term
.
.
Original source:
Yu-Han Huang.
Influence of Nonalcoholic Fatty Liver Disease with Elevated Liver Enzyme Levels on Risk of Cirrhosis and Hepatocellular Carcinoma.
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